In mouse V1 L2/3, paired-recording amplitudes are highly skewed (log-normal-lik…

{
  "n": 0,
  "doi": "10.1038/nature14182",
  "claim": "In mouse V1 L2/3, paired-recording amplitudes are highly skewed (log-normal-like) and the few strong E→E connections occur between neurons with most correlated visual responses, while weak connections link uncorrelated neurons.",
  "cite_key": "Cossell2015",
  "evidence": "In vivo two-photon imaging followed by in vitro multiple paired recordings of L2/3 pyramidal neurons in mouse V1.",
  "effect_size": "Excitatory connection amplitudes span >2 orders of magnitude; majority of local excitation provided by rare strong inputs from similarly tuned neighbors.",
  "text_access": "abstract_only",
  "study_system": "mouse V1 L2/3, paired-recording E→E strength + 2P functional imaging",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Here we reveal that the strength of connections between layer 2/3 (L2/3) pyramidal neurons in mouse primary visual cortex (V1) obeys a simple rule--the few strong connections occur between neurons with most correlated responses, while only weak connections link neurons with uncorrelated responses. Moreover, we show that strong and reciprocal connections occur between cells with similar spatial receptive field structure.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/nature09880",
    "10.1038/nature12015",
    "10.1016/j.xinn.2024.100735"
  ],
  "effect_size_source_sentence": "Excitatory connection amplitudes between pairs of cortical neurons vary over two orders of magnitude, comprising only very few strong connections among many weaker ones."
}

[
  "paper:paper-c4ad527c9bfb"
]

Here we reveal that the strength of connections between layer 2/3 (L2/3) pyramidal neurons in mouse primary visual cortex (V1) obeys a simple rule--the few strong connections occur between neurons with most correlated responses, while only weak connections link neurons with uncorrelated responses. Moreover, we show that strong and reciprocal connections occur between cells with similar spatial receptive field struct...

[
  {
    "ref": "paper:paper-c4ad527c9bfb"
  }
]

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}