Version history

{
  "scope": "Mouse olfactory bulb + piriform cortex; high-throughput barcoded projection mapping.",
  "claim_text": "High-throughput barcode sequencing of 30,433 mouse piriform-cortex output neurons reveals that olfactory-cortex long-range projections are spatially structured along the anterior–posterior axis, matching their olfactory-bulb inputs, in contrast to the prior 'random connectivity' view of olfactory cortex.",
  "raw_fields": {
    "n": 30433,
    "doi": "10.1016/j.cell.2022.09.038",
    "claim": "High-throughput barcode sequencing of 30,433 mouse piriform-cortex output neurons reveals that olfactory-cortex long-range projections are spatially structured along the anterior–posterior axis, matching their olfactory-bulb inputs, in contrast to the prior 'random connectivity' view of olfactory cortex.",
    "cite_key": "Chen2022",
    "evidence": "MAPseq/BARseq-class barcode sequencing of 5,309 olfactory bulb and 30,433 piriform cortex output neurons in mouse; statistical analysis of projection–origin axis correspondence.",
    "effect_size": "30,433 piriform output neurons + 5,309 bulb neurons; spatially matched A-P projection structure.",
    "text_access": "fulltext",
    "study_system": "Mouse olfactory bulb + piriform cortex; high-throughput barcoded projection mapping.",
    "argument_role": "supporting",
    "replication_status": "replicated",
    "claim_source_sentence": "Surprisingly, statistical analysis of this much larger dataset revealed that the olfactory cortex connectivity is spatially structured.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [
      "10.1016/j.cell.2019.09.023"
    ],
    "effect_size_source_sentence": "Here, we used high-throughput sequencing-based neuroanatomical techniques to analyze the projections of 5,309 mouse olfactory bulb and 30,433 piriform cortex output neurons at single-cell resolution."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "effect_size": "30,433 piriform output neurons + 5,309 bulb neurons; spatially matched A-P projection structure.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-77c873150807"
  ],
  "source_span": "Surprisingly, statistical analysis of this much larger dataset revealed that the olfactory cortex connectivity is spatially structured.",
  "study_system": "Mouse olfactory bulb + piriform cortex; high-throughput barcoded projection mapping.",
  "evidence_refs": [
    {
      "ref": "paper:paper-77c873150807"
    }
  ],
  "section_title": "8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "MAPseq/BARseq-class barcode sequencing of 5,309 olfactory bulb and 30,433 piriform cortex output neurons in mouse; statistical analysis of projection–origin axis correspondence.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}