Details

scope
Mouse olfactory bulb + piriform cortex; high-throughput barcoded projection mapping.
section_id
section_08
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
effect_size
30,433 piriform output neurons + 5,309 bulb neurons; spatially matched A-P projection structure.
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
source_span
Surprisingly, statistical analysis of this much larger dataset revealed that the olfactory cortex connectivity is spatially structured.
study_system
Mouse olfactory bulb + piriform cortex; high-throughput barcoded projection mapping.
section_title
8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
evidence_summary
MAPseq/BARseq-class barcode sequencing of 5,309 olfactory bulb and 30,433 piriform cortex output neurons in mouse; statistical analysis of projection–origin axis correspondence.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replicated
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
High-throughput barcode sequencing of 30,433 mouse piriform-cortex output neurons reveals that olfactory-cortex long-range projections are spatially structured along the anterior–posterior axis, matching their olfactory-bulb inputs, in contrast to the prior 'random connectivity' view of olfactory cortex.
raw_fields
{
  "n": 30433,
  "doi": "10.1016/j.cell.2022.09.038",
  "claim": "High-throughput barcode sequencing of 30,433 mouse piriform-cortex output neurons reveals that olfactory-cortex long-range projections are spatially structured along the anterior–posterior axis, matching their olfactory-bulb inputs, in contrast to the prior 'random connectivity' view of olfactory cortex.",
  "cite_key": "Chen2022",
  "evidence": "MAPseq/BARseq-class barcode sequencing of 5,309 olfactory bulb and 30,433 piriform cortex output neurons in mouse; statistical analysis of projection–origin axis correspondence.",
  "effect_size": "30,433 piriform output neurons + 5,309 bulb neurons; spatially matched A-P projection structure.",
  "text_access": "fulltext",
  "study_system": "Mouse olfactory bulb + piriform cortex; high-throughput barcoded projection mapping.",
  "argument_role": "supporting",
  "replication_status": "replicated",
  "claim_source_sentence": "Surprisingly, statistical analysis of this much larger dataset revealed that the olfactory cortex connectivity is spatially structured.",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [
    "10.1016/j.cell.2019.09.023"
  ],
  "effect_size_source_sentence": "Here, we used high-throughput sequencing-based neuroanatomical techniques to analyze the projections of 5,309 mouse olfactory bulb and 30,433 piriform cortex output neurons at single-cell resolution."
}
source_refs
[
  "paper:paper-77c873150807"
]
evidence_refs
[
  {
    "ref": "paper:paper-77c873150807"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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