Version history

{
  "scope": "mouse motor cortex projection neurons, brain-wide serial two-photon imaging platform",
  "claim_text": "A high-speed two-photon microscope integrated with a tissue vibratome (TissueCyte-style) and large-scale image computation enables three-dimensional reconstruction of complete long-range axonal arbors of multiple motor-cortex neurons within a single mouse brain at ~100 nm axon resolution.",
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    "n": null,
    "doi": "10.7554/elife.10566",
    "claim": "A high-speed two-photon microscope integrated with a tissue vibratome (TissueCyte-style) and large-scale image computation enables three-dimensional reconstruction of complete long-range axonal arbors of multiple motor-cortex neurons within a single mouse brain at ~100 nm axon resolution.",
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    "claim_source_sentence": "We introduce a platform for high-resolution, three-dimensional fluorescence imaging of complete tissue volumes that enables the visualization and reconstruction of long-range axonal arbors... We demonstrate the power of this approach by reconstructing the axonal arbors of multiple neurons in the motor cortex across a single mouse brain.",
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    "effect_size_source_sentence": null
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  "section_id": "section_02",
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  "source_span": "We introduce a platform for high-resolution, three-dimensional fluorescence imaging of complete tissue volumes that enables the visualization and reconstruction of long-range axonal arbors... We demonstrate the power of this approach by reconstructing the axonal arbors of multiple neurons in the motor cortex across a single mouse brain.",
  "study_system": "mouse motor cortex projection neurons, brain-wide serial two-photon imaging platform",
  "evidence_refs": [
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  "section_title": "2. Mouse-cortex anatomy primer — areal map, layer structure, projection-class nomenclature (IT / PT / CT), tools available for E→E dissection (paired patch, Cre lines, two-photon-targeted patch, optogenetics, EM reconstruction)",
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    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
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    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
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  "evidence_summary": "Integrated two-photon serial vibratome microscope plus computational reconstruction pipeline applied to sparsely labeled mouse motor cortex projection neurons.",
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}