- claim_text
A high-speed two-photon microscope integrated with a tissue vibratome (TissueCyte-style) and large-scale image computation enables three-dimensional reconstruction of complete long-range axonal arbors of multiple motor-cortex neurons within a single mouse brain at ~100 nm axon resolution.
- raw_fields
{
"n": null,
"doi": "10.7554/elife.10566",
"claim": "A high-speed two-photon microscope integrated with a tissue vibratome (TissueCyte-style) and large-scale image computation enables three-dimensional reconstruction of complete long-range axonal arbors of multiple motor-cortex neurons within a single mouse brain at ~100 nm axon resolution.",
"cite_key": "Economo2016",
"evidence": "Integrated two-photon serial vibratome microscope plus computational reconstruction pipeline applied to sparsely labeled mouse motor cortex projection neurons.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mouse motor cortex projection neurons, brain-wide serial two-photon imaging platform",
"argument_role": "supporting",
"replication_status": "replication_unknown",
"claim_source_sentence": "We introduce a platform for high-resolution, three-dimensional fluorescence imaging of complete tissue volumes that enables the visualization and reconstruction of long-range axonal arbors... We demonstrate the power of this approach by reconstructing the axonal arbors of multiple neurons in the motor cortex across a single mouse brain.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:b99d7c4a-9270-42c0-b083-2109f9c1eabf"
]
- source_span
We introduce a platform for high-resolution, three-dimensional fluorescence imaging of complete tissue volumes that enables the visualization and reconstruction of long-range axonal arbors... We demonstrate the power of this approach by reconstructing the axonal arbors of multiple neurons in the motor cortex across a single mouse brain.
- evidence_refs
[
{
"ref": "paper:b99d7c4a-9270-42c0-b083-2109f9c1eabf"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}