Version history

{
  "scope": "human, MTG (adult, snRNA-seq)",
  "claim_text": "VIP is the most transcriptomically diverse interneuron subclass in human middle temporal gyrus (21 types), with many VIP types enriched in upper layers and several closely related to a layer 1–2 LAMP5/PAX6 (L1 LAMP5 NMBR) type — indicating extensive intra-VIP molecular heterogeneity in human cortex.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/s41586-019-1506-7",
    "claim": "VIP is the most transcriptomically diverse interneuron subclass in human middle temporal gyrus (21 types), with many VIP types enriched in upper layers and several closely related to a layer 1–2 LAMP5/PAX6 (L1 LAMP5 NMBR) type — indicating extensive intra-VIP molecular heterogeneity in human cortex.",
    "title": null,
    "cite_key": "Hodge2019",
    "evidence": "snRNA-seq of human MTG (8 donors, ~16,000 nuclei); 45 GABAergic types parsed; ADARB2-branch organization with LAMP5/PAX6 vs VIP subclasses.",
    "effect_size": "21 transcriptomically distinct VIP types in human MTG (vs fewer in mouse)",
    "figure_data": [
      {
        "type": "cell_type_count",
        "unit": "types",
        "value": 21,
        "metric": "Number of transcriptomic VIP types in human MTG",
        "source": "Hodge 2019 Fig. 3a",
        "context": "Most diverse interneuron subclass; many enriched in upper layers"
      }
    ],
    "text_access": "fulltext",
    "study_system": "human, MTG (adult, snRNA-seq)",
    "_source_cluster": "cluster_02_development_lineage",
    "replication_status": "primary",
    "_source_cluster_index": 100,
    "claim_source_sentence": "VIP was the most diverse subclass (21 types), with many types enriched in upper layers ( Fig. 3a ). Several VIP types were closely related to the LAMP5/PAX6 type L1 LAMP5 NMBR and localized to L1-L2.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "VIP was the most diverse subclass (21 types), with many types enriched in upper layers ( Fig. 3a )."
  },
  "section_id": "section_03",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "effect_size": "21 transcriptomically distinct VIP types in human MTG (vs fewer in mouse)",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-03-development",
  "source_kind": "review_finding",
  "source_path": "evidence/section_03_evidence_package.json",
  "source_refs": [
    "paper:paper-pm-31435019"
  ],
  "source_span": "VIP was the most diverse subclass (21 types), with many types enriched in upper layers ( Fig. 3a ). Several VIP types were closely related to the LAMP5/PAX6 type L1 LAMP5 NMBR and localized to L1-L2.",
  "study_system": "human, MTG (adult, snRNA-seq)",
  "evidence_refs": [
    {
      "ref": "paper:paper-pm-31435019"
    }
  ],
  "section_title": "Developmental Origins and Postnatal Maturation",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "snRNA-seq of human MTG (8 donors, ~16,000 nuclei); 45 GABAergic types parsed; ADARB2-branch organization with LAMP5/PAX6 vs VIP subclasses.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "primary",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-03-development",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}