Version history

{
  "scope": "PD patients with bilateral STN-DBS and persistent freezing of gait (n=7)",
  "claim_text": "Compared with conventional 130 Hz STN-DBS, 60 Hz stimulation reduced laryngeal aspiration frequency by 57% and perceived swallowing difficulty by 80%, with parallel improvement in freezing of gait.",
  "raw_fields": {
    "n": 7,
    "doi": "10.1212/wnl.0000000000001184",
    "claim": "Compared with conventional 130 Hz STN-DBS, 60 Hz stimulation reduced laryngeal aspiration frequency by 57% and perceived swallowing difficulty by 80%, with parallel improvement in freezing of gait.",
    "cite_key": "Xie2015",
    "evidence": "Randomized, double-blinded MBS swallowing assessment under 130 Hz, 60 Hz, and OFF in PD patients with persistent FOG, with 6-week chronic 60 Hz follow-up.",
    "effect_size": "57% aspiration reduction; 80% swallowing-difficulty reduction",
    "text_access": "fulltext",
    "study_system": "PD patients with bilateral STN-DBS and persistent freezing of gait (n=7)",
    "source_cluster_id": "cluster_13",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "We found that the low-stimulation\nfrequency of DBS at 60 Hz improved swallowing\nfunction compared with 130 Hz, by both the\nobjective MBS study (significantly decreasing\naspiration frequency by 57%) and the subjective\nquestionnaire (significantly decreasing swallowing\ndifficulty by 80%), a conclusion of significant\nclinical impact.",
    "replication_evidence_dois": [
      "10.1186/s40035-017-0083-7",
      "10.1002/mds.26837"
    ],
    "effect_size_source_sentence": "We found that the low-stimulation\nfrequency of DBS at 60 Hz improved swallowing\nfunction compared with 130 Hz, by both the\nobjective MBS study (significantly decreasing\naspiration frequency by 57%) and the subjective\nquestionnaire (significantly decreasing swallowing\ndifficulty by 80%), a conclusion of significant\nclinical impact."
  },
  "section_id": "section_14",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json",
  "effect_size": "57% aspiration reduction; 80% swallowing-difficulty reduction",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-14",
  "source_kind": "review_finding",
  "source_path": "evidence/section_14_evidence_package.json",
  "source_refs": [
    "paper:paper-c2d23dd91813"
  ],
  "source_span": "We found that the low-stimulation frequency of DBS at 60 Hz improved swallowing function compared with 130 Hz, by both the objective MBS study (significantly decreasing aspiration frequency by 57%) and the subjective questionnaire (significantly decreasing swallowing difficulty by 80%), a conclusion of significant clinical impact.",
  "study_system": "PD patients with bilateral STN-DBS and persistent freezing of gait (n=7)",
  "evidence_refs": [
    {
      "ref": "paper:paper-c2d23dd91813"
    }
  ],
  "section_title": "Loop Dysfunction in Neurological and Psychiatric Disease",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Randomized, double-blinded MBS swallowing assessment under 130 Hz, 60 Hz, and OFF in PD patients with persistent FOG, with 6-week chronic 60 Hz follow-up.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-14",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}