Version history

{
  "scope": "acute mouse hippocampal CA1 slices; paired patch-clamp + ChR2 optogenetics",
  "claim_text": "VIP+/calretinin+ type-3 interneuron-specific (IS3) cells in CA1 oriens/alveus selectively innervate oriens-lacunosum moleculare (OLM) cells via dendritic synapses; synchronous IS3 spikes control OLM firing rate and spike timing, implicating IS3 cells in temporal patterning of theta-rhythmic OLM output.",
  "raw_fields": {
    "n": null,
    "doi": "10.1523/jneurosci.3813-13.2014",
    "pmid": "",
    "year": 2014,
    "claim": "VIP+/calretinin+ type-3 interneuron-specific (IS3) cells in CA1 oriens/alveus selectively innervate oriens-lacunosum moleculare (OLM) cells via dendritic synapses; synchronous IS3 spikes control OLM firing rate and spike timing, implicating IS3 cells in temporal patterning of theta-rhythmic OLM output.",
    "pmcid": "",
    "title": "Dendritic Inhibition Provided by Interneuron-Specific Cells Controls the Firing Rate and Timing of the Hippocampal Feedback Inhibitory Circuitry",
    "authors": "",
    "journal": "",
    "cite_key": "Tyan2014",
    "evidence": "Dual patch-clamp + targeted optogenetics in acute mouse hippocampal slices; unitary IPSC analysis at IS3-OLM synapses.",
    "cluster_id": "cluster_09_oscillations",
    "effect_size": "single-spike convergent IS input controls OLM firing rate/timing",
    "figure_data": [],
    "text_access": "abstract_only",
    "study_system": "acute mouse hippocampal CA1 slices; paired patch-clamp + ChR2 optogenetics",
    "cited_by_count": 155,
    "_source_cluster": "cluster_09_oscillations",
    "replication_status": "independently_replicated",
    "_source_cluster_index": 8,
    "claim_source_sentence": "Moreover, the synchronous generation of a single spike in several IS cells that converged onto a single OLM controlled the firing rate and timing of OLM interneurons.",
    "replication_evidence_dois": [
      "10.1523/jneurosci.16-10-03397.1996",
      "10.3389/fncel.2010.00130",
      "10.7554/elife.46816"
    ],
    "effect_size_source_sentence": "the synchronous generation of a single spike in several IS cells that converged onto a single OLM controlled the firing rate and timing of OLM interneurons."
  },
  "section_id": "section_10",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json",
  "effect_size": "single-spike convergent IS input controls OLM firing rate/timing",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-10-oscillatory-dynamics",
  "source_kind": "review_finding",
  "source_path": "evidence/section_10_evidence_package.json",
  "source_refs": [
    "paper:paper-6b0c417962ed"
  ],
  "source_span": "Moreover, the synchronous generation of a single spike in several IS cells that converged onto a single OLM controlled the firing rate and timing of OLM interneurons.",
  "study_system": "acute mouse hippocampal CA1 slices; paired patch-clamp + ChR2 optogenetics",
  "evidence_refs": [
    {
      "ref": "paper:paper-6b0c417962ed"
    }
  ],
  "section_title": "Oscillatory Dynamics and Temporal Coordination",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Dual patch-clamp + targeted optogenetics in acute mouse hippocampal slices; unitary IPSC analysis at IS3-OLM synapses.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-10-oscillatory-dynamics",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}