Version history

{
  "scope": "mouse cortex (review)",
  "claim_text": "Two electrophysiologically distinct 'late-spiking' CGE-derived 5HT3aR multipolar interneuron subtypes (LS1/LS2; also termed dense plexus and initial-adapting cells) co-express reelin but not VIP, providing a molecular/physiological signature for non-VIP 5HT3aR interneurons.",
  "raw_fields": {
    "n": null,
    "doi": "10.1002/dneu.20853",
    "claim": "Two electrophysiologically distinct 'late-spiking' CGE-derived 5HT3aR multipolar interneuron subtypes (LS1/LS2; also termed dense plexus and initial-adapting cells) co-express reelin but not VIP, providing a molecular/physiological signature for non-VIP 5HT3aR interneurons.",
    "title": null,
    "cite_key": "Rudy2011",
    "evidence": "Multiple studies (Butt 2005, Miyoshi 2007/2010, Lee 2010) characterizing CGE-derived 5HT3aR interneurons by morphology and physiology in mouse cortex.",
    "effect_size": "2 late-spiking subtypes (LS1/LS2) within CGE-derived 5HT3aR/Reln+/VIP- population",
    "figure_data": [],
    "text_access": "fulltext",
    "study_system": "mouse cortex (review)",
    "_source_cluster": "cluster_02_development_lineage",
    "replication_status": "replicated",
    "_source_cluster_index": 86,
    "claim_source_sentence": "Studies of CGE-derived and 5HT3aR interneurons have described two types of \"late-spiking\" cells, both of which are multipolar, express reelin but not VIP, and have been termed LS1 and LS2 (also described as \"dense plexus cells\" and initial adapting) ( Butt et al., 2005 ; Miyoshi et al., 2007 ; Lee et al., 2010 ; Miyoshi et al., 2010 ).",
    "replication_evidence_dois": [
      "10.1016/j.neuron.2005.09.034",
      "10.1523/jneurosci.1807-07.2007",
      "10.1523/jneurosci.1869-10.2010"
    ],
    "effect_size_source_sentence": "Studies of CGE-derived and 5HT3aR interneurons have described two types of \"late-spiking\" cells, both of which are multipolar, express reelin but not VIP, and have been termed LS1 and LS2 (also described as \"dense plexus cells\" and initial adapting) ( Butt et al., 2005 ; Miyoshi et al., 2007 ; Lee et al., 2010 ; Miyoshi et al., 2010 )."
  },
  "section_id": "section_03",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "effect_size": "2 late-spiking subtypes (LS1/LS2) within CGE-derived 5HT3aR/Reln+/VIP- population",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-03-development",
  "source_kind": "review_finding",
  "source_path": "evidence/section_03_evidence_package.json",
  "source_refs": [
    "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
  ],
  "source_span": "Studies of CGE-derived and 5HT3aR interneurons have described two types of \"late-spiking\" cells, both of which are multipolar, express reelin but not VIP, and have been termed LS1 and LS2 (also described as \"dense plexus cells\" and initial adapting) ( Butt et al., 2005 ; Miyoshi et al., 2007 ; Lee et al., 2010 ; Miyoshi et al., 2010 ).",
  "study_system": "mouse cortex (review)",
  "evidence_refs": [
    {
      "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
    }
  ],
  "section_title": "Developmental Origins and Postnatal Maturation",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Multiple studies (Butt 2005, Miyoshi 2007/2010, Lee 2010) characterizing CGE-derived 5HT3aR interneurons by morphology and physiology in mouse cortex.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-03-development",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}