Two electrophysiologically distinct 'late-spiking' CGE-derived 5HT3aR multipola…

Two electrophysiologically distinct 'late-spiking' CGE-derived 5HT3aR multipolar interneuron subtypes (LS1/LS2; also termed dense plexus and initial-adapting cells) co-express reelin but not VIP, providing a molecular/physiological signature for non-VIP 5HT3aR interneurons.

{
  "n": null,
  "doi": "10.1002/dneu.20853",
  "claim": "Two electrophysiologically distinct 'late-spiking' CGE-derived 5HT3aR multipolar interneuron subtypes (LS1/LS2; also termed dense plexus and initial-adapting cells) co-express reelin but not VIP, providing a molecular/physiological signature for non-VIP 5HT3aR interneurons.",
  "title": null,
  "cite_key": "Rudy2011",
  "evidence": "Multiple studies (Butt 2005, Miyoshi 2007/2010, Lee 2010) characterizing CGE-derived 5HT3aR interneurons by morphology and physiology in mouse cortex.",
  "effect_size": "2 late-spiking subtypes (LS1/LS2) within CGE-derived 5HT3aR/Reln+/VIP- population",
  "figure_data": [],
  "text_access": "fulltext",
  "study_system": "mouse cortex (review)",
  "_source_cluster": "cluster_02_development_lineage",
  "replication_status": "replicated",
  "_source_cluster_index": 86,
  "claim_source_sentence": "Studies of CGE-derived and 5HT3aR interneurons have described two types of \"late-spiking\" cells, both of which are multipolar, express reelin but not VIP, and have been termed LS1 and LS2 (also described as \"dense plexus cells\" and initial adapting) ( Butt et al., 2005 ; Miyoshi et al., 2007 ; Lee et al., 2010 ; Miyoshi et al., 2010 ).",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2005.09.034",
    "10.1523/jneurosci.1807-07.2007",
    "10.1523/jneurosci.1869-10.2010"
  ],
  "effect_size_source_sentence": "Studies of CGE-derived and 5HT3aR interneurons have described two types of \"late-spiking\" cells, both of which are multipolar, express reelin but not VIP, and have been termed LS1 and LS2 (also described as \"dense plexus cells\" and initial adapting) ( Butt et al., 2005 ; Miyoshi et al., 2007 ; Lee et al., 2010 ; Miyoshi et al., 2010 )."
}

[
  "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
]

Studies of CGE-derived and 5HT3aR interneurons have described two types of "late-spiking" cells, both of which are multipolar, express reelin but not VIP, and have been termed LS1 and LS2 (also described as "dense plexus cells" and initial adapting) ( Butt et al., 2005 ; Miyoshi et al., 2007 ; Lee et al., 2010 ; Miyoshi et al., 2010 ).

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    "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
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  "notes": [
    "Local review repositories are read-only inputs.",
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  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}