Version history

{
  "scope": "mouse mPFC L1b VIP-Cre × Ai14 acute slices",
  "claim_text": "In medial PFC L1b, VIP+ interneurons display bitufted or bipolar morphology and a heterogeneous mix of non-fast-spiking (53%), irregular-spiking (29%), and fast-adapting (18%) firing patterns (n=17 cells, 8 mice), with thalamic MD inputs preferentially driving VIP+ cells over NDNF+ cells through higher intrinsic excitability.",
  "raw_fields": {
    "n": 17,
    "doi": "10.1016/j.neuron.2020.10.031",
    "claim": "In medial PFC L1b, VIP+ interneurons display bitufted or bipolar morphology and a heterogeneous mix of non-fast-spiking (53%), irregular-spiking (29%), and fast-adapting (18%) firing patterns (n=17 cells, 8 mice), with thalamic MD inputs preferentially driving VIP+ cells over NDNF+ cells through higher intrinsic excitability.",
    "title": null,
    "cite_key": "Anastasiades2021a",
    "evidence": "VIP-Cre × Ai14 mouse mPFC L1b acute slices, whole-cell patch from biocytin-filled VIP+ cells; circuit mapping with optogenetics from MD/VM thalamic inputs",
    "effect_size": "VIP+ L1b firing class proportions: NFS 9/17 (53%), IS 5/17 (29%), fAD 3/17 (18%)",
    "text_access": "fulltext",
    "study_system": "mouse mPFC L1b VIP-Cre × Ai14 acute slices",
    "_source_cluster": "cluster_04_intrinsic_electrophysiology",
    "replication_status": "replicated",
    "_source_cluster_index": 19,
    "claim_source_sentence": "We found VIP+ cells in L1b had bitufted or bipolar morphologies, along with non-fast-spiking (NFS), irregular-spiking (IS), or fast-adapting (fAD) firing properties (n = 17 VIP+ cells, 8 mice; NFS = 9/17, IS = 5/17, fAD = 3/17)",
    "replication_evidence_dois": [
      "10.7554/elife.46846",
      "10.1126/science.adf6484"
    ],
    "effect_size_source_sentence": "We found VIP+ cells in L1b had bitufted or bipolar morphologies, along with non-fast-spiking (NFS), irregular-spiking (IS), or fast-adapting (fAD) firing properties (n = 17 VIP+ cells, 8 mice; NFS = 9/17, IS = 5/17, fAD = 3/17)"
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "effect_size": "VIP+ L1b firing class proportions: NFS 9/17 (53%), IS 5/17 (29%), fAD 3/17 (18%)",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-7227d2a3ed3e"
  ],
  "source_span": "We found VIP+ cells in L1b had bitufted or bipolar morphologies, along with non-fast-spiking (NFS), irregular-spiking (IS), or fast-adapting (fAD) firing properties (n = 17 VIP+ cells, 8 mice; NFS = 9/17, IS = 5/17, fAD = 3/17)",
  "study_system": "mouse mPFC L1b VIP-Cre × Ai14 acute slices",
  "evidence_refs": [
    {
      "ref": "paper:paper-7227d2a3ed3e"
    }
  ],
  "section_title": "Intrinsic Electrophysiology",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "VIP-Cre × Ai14 mouse mPFC L1b acute slices, whole-cell patch from biocytin-filled VIP+ cells; circuit mapping with optogenetics from MD/VM thalamic inputs",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}