Details
- scope
- mouse mPFC L1b VIP-Cre × Ai14 acute slices
- section_id
- section_05
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
- effect_size
- VIP+ L1b firing class proportions: NFS 9/17 (53%), IS 5/17 (29%), fAD 3/17 (18%)
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-05-electrophysiology
- source_kind
- review_finding
- source_path
- evidence/section_05_evidence_package.json
- source_span
- We found VIP+ cells in L1b had bitufted or bipolar morphologies, along with non-fast-spiking (NFS), irregular-spiking (IS), or fast-adapting (fAD) firing properties (n = 17 VIP+ cells, 8 mice; NFS = 9/17, IS = 5/17, fAD = 3/17)
- study_system
- mouse mPFC L1b VIP-Cre × Ai14 acute slices
- section_title
- Intrinsic Electrophysiology
- evidence_summary
- VIP-Cre × Ai14 mouse mPFC L1b acute slices, whole-cell patch from biocytin-filled VIP+ cells; circuit mapping with optogenetics from MD/VM thalamic inputs
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-05-electrophysiology
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- claim_text
In medial PFC L1b, VIP+ interneurons display bitufted or bipolar morphology and a heterogeneous mix of non-fast-spiking (53%), irregular-spiking (29%), and fast-adapting (18%) firing patterns (n=17 cells, 8 mice), with thalamic MD inputs preferentially driving VIP+ cells over NDNF+ cells through higher intrinsic excitability.
- raw_fields
{ "n": 17, "doi": "10.1016/j.neuron.2020.10.031", "claim": "In medial PFC L1b, VIP+ interneurons display bitufted or bipolar morphology and a heterogeneous mix of non-fast-spiking (53%), irregular-spiking (29%), and fast-adapting (18%) firing patterns (n=17 cells, 8 mice), with thalamic MD inputs preferentially driving VIP+ cells over NDNF+ cells through higher intrinsic excitability.", "title": null, "cite_key": "Anastasiades2021a", "evidence": "VIP-Cre × Ai14 mouse mPFC L1b acute slices, whole-cell patch from biocytin-filled VIP+ cells; circuit mapping with optogenetics from MD/VM thalamic inputs", "effect_size": "VIP+ L1b firing class proportions: NFS 9/17 (53%), IS 5/17 (29%), fAD 3/17 (18%)", "text_access": "fulltext", "study_system": "mouse mPFC L1b VIP-Cre × Ai14 acute slices", "_source_cluster": "cluster_04_intrinsic_electrophysiology", "replication_status": "replicated", "_source_cluster_index": 19, "claim_source_sentence": "We found VIP+ cells in L1b had bitufted or bipolar morphologies, along with non-fast-spiking (NFS), irregular-spiking (IS), or fast-adapting (fAD) firing properties (n = 17 VIP+ cells, 8 mice; NFS = 9/17, IS = 5/17, fAD = 3/17)", "replication_evidence_dois": [ "10.7554/elife.46846", "10.1126/science.adf6484" ], "effect_size_source_sentence": "We found VIP+ cells in L1b had bitufted or bipolar morphologies, along with non-fast-spiking (NFS), irregular-spiking (IS), or fast-adapting (fAD) firing properties (n = 17 VIP+ cells, 8 mice; NFS = 9/17, IS = 5/17, fAD = 3/17)" }- source_refs
[ "paper:paper-7227d2a3ed3e" ]
- evidence_refs
[ { "ref": "paper:paper-7227d2a3ed3e" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }