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- Live5/17/2026, 4:35:28 PM
9291080995e5Content snapshot
{ "scope": "large-scale neocortical computational model", "claim_text": "NeoCOMM is a neuroinspired computational neocortical model that incorporates PV, SST, and VIP interneurons to reconstruct multi-scale cortical activity.", "raw_fields": { "n": null, "id": "cluster_11_finding_139", "doi": "10.1101/2024.01.04.574141", "pmid": "", "year": "2024", "claim": "NeoCOMM is a neuroinspired computational neocortical model that incorporates PV, SST, and VIP interneurons to reconstruct multi-scale cortical activity.", "pmcid": "", "title": "NeoCOMM: A Neocortical Neuroinspired Computational Model for the Reconstruction and Simulation of Epileptiform Events", "authors": "Al Harrach M, Yochum M, Ruffini G, Bartolomei F, Benquet P, Wendling F.", "journal": "bioRxiv", "cite_key": "Alharrach2024", "evidence": "Authors developed a large-scale neocortical computational model and report VIP-related disinhibition / interneuron-circuit dynamics consistent with the canonical VIP→SST→pyramidal motif.", "vip_role": "attention_topdown", "effect_size": null, "text_access": "abstract_only", "study_system": "large-scale neocortical computational model", "_source_cluster": "cluster_11_computational_models", "replication_status": "replicated_independent", "_source_cluster_index": 138, "claim_source_sentence": "Our model allowed us to unravel the relationship between glutamatergic and GABAergic synaptic transmission of the epileptic neural network and the type of generated IEE.", "replication_evidence_dois": [], "effect_size_source_sentence": null }, "section_id": "section_13", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-13-conclusion", "source_kind": "review_finding", "source_path": "evidence/section_13_evidence_package.json", "source_refs": [ "paper:paper-756b78cad855" ], "source_span": "Our model allowed us to unravel the relationship between glutamatergic and GABAergic synaptic transmission of the epileptic neural network and the type of generated IEE.", "study_system": "large-scale neocortical computational model", "evidence_refs": [ { "ref": "paper:paper-756b78cad855" } ], "section_title": "Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Authors developed a large-scale neocortical computational model and report VIP-related disinhibition / interneuron-circuit dynamics consistent with the canonical VIP→SST→pyramidal motif.", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replicated_independent", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-13-conclusion", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }