NeoCOMM is a neuroinspired computational neocortical model that incorporates PV…

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  "doi": "10.1101/2024.01.04.574141",
  "pmid": "",
  "year": "2024",
  "claim": "NeoCOMM is a neuroinspired computational neocortical model that incorporates PV, SST, and VIP interneurons to reconstruct multi-scale cortical activity.",
  "pmcid": "",
  "title": "NeoCOMM: A Neocortical Neuroinspired Computational Model for the Reconstruction and Simulation of Epileptiform Events",
  "authors": "Al Harrach M, Yochum M, Ruffini G, Bartolomei F, Benquet P, Wendling F.",
  "journal": "bioRxiv",
  "cite_key": "Alharrach2024",
  "evidence": "Authors developed a large-scale neocortical computational model and report VIP-related disinhibition / interneuron-circuit dynamics consistent with the canonical VIP→SST→pyramidal motif.",
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  "study_system": "large-scale neocortical computational model",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "replicated_independent",
  "_source_cluster_index": 138,
  "claim_source_sentence": "Our model allowed us to unravel the relationship between glutamatergic and GABAergic synaptic transmission of the epileptic neural network and the type of generated IEE.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

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