Version history

{
  "scope": "Mouse primary visual cortex; anterograde + retrograde viral tracing of horizontal connectivity; M2 muscarinic receptor immunolabelling",
  "claim_text": "Within mouse V1, long-range horizontal connections are patchy and terminate preferentially in M2 muscarinic-acetylcholine-receptor-negative interpatches, overlapping with apical dendrites of L2/3 and L5 projection cells to form module-selective horizontal–vertical loops.",
  "raw_fields": {
    "n": 0,
    "doi": "10.3389/fnana.2024.1364675",
    "claim": "Within mouse V1, long-range horizontal connections are patchy and terminate preferentially in M2 muscarinic-acetylcholine-receptor-negative interpatches, overlapping with apical dendrites of L2/3 and L5 projection cells to form module-selective horizontal–vertical loops.",
    "cite_key": "Burkhalter2024",
    "evidence": "Combined anterograde and retrograde viral tracing in mouse V1 with cross-registration against M2 muscarinic-receptor patches.",
    "effect_size": "Long-range horizontal contacts cluster in M2- interpatches, overlapping apical dendrites of L2/3 and L5 projection cells (qualitative).",
    "text_access": "abstract_only",
    "study_system": "Mouse primary visual cortex; anterograde + retrograde viral tracing of horizontal connectivity; M2 muscarinic receptor immunolabelling",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "The long connections were patchy and terminated preferentially in M2 muscarinic acetylcholine receptor-negative (M2-) interpatches. Anterogradely labeled inputs overlapped in M2-interpatches with apical dendrites of retrogradely labeled L2/3 and L5 cells, forming module-selective loops between topographically distant locations.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "Long-range horizontal contacts cluster in M2- interpatches, overlapping apical dendrites of L2/3 and L5 projection cells (qualitative).",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-236876dbc518"
  ],
  "source_span": "The long connections were patchy and terminated preferentially in M2 muscarinic acetylcholine receptor-negative (M2-) interpatches. Anterogradely labeled inputs overlapped in M2-interpatches with apical dendrites of retrogradely labeled L2/3 and L5 cells, forming module-selective loops between topographically distant locations.",
  "study_system": "Mouse primary visual cortex; anterograde + retrograde viral tracing of horizontal connectivity; M2 muscarinic receptor immunolabelling",
  "evidence_refs": [
    {
      "ref": "paper:paper-236876dbc518"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Combined anterograde and retrograde viral tracing in mouse V1 with cross-registration against M2 muscarinic-receptor patches.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}