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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse M1", "claim_text": "2a ) were performed on wild-type C57Bl/6 ( n = 27), Viaat -Cre/Ai9 (vesicular inhibitory amino acid transporter, encoded by the Slc32a1 gene, n = 24), Sst -Cre/Ai9 (somatostatin, n = 75), Vip -Cre/Ai9 (vasoactive intestinal polypeptide, n = 46), Pvalb -Cre/Ai9 (parvalbumin, n = 76), Npy -Cre/Ai9 (neuropeptide Y, n = 2), Vipr2 -Cre/Ai9 (vasoactive intestinal peptide receptor 2, n = 7), Scl17a8 -Cre/Ai9 (VGLUT3, vesicular glutamate transporter 3, n = 6), Gnb4 -Cre/Ai9 ( n = 1), and Slc17a8 -iCre/Ai9 ( n = 2) mice.", "raw_fields": { "n": 27, "doi": "10.1038/s41586-020-2907-3", "year": "2020", "claim": "2a ) were performed on wild-type C57Bl/6 ( n = 27), Viaat -Cre/Ai9 (vesicular inhibitory amino acid transporter, encoded by the Slc32a1 gene, n = 24), Sst -Cre/Ai9 (somatostatin, n = 75), Vip -Cre/Ai9 (vasoactive intestinal polypeptide, n = 46), Pvalb -Cre/Ai9 (parvalbumin, n = 76), Npy -Cre/Ai9 (neuropeptide Y, n = 2), Vipr2 -Cre/Ai9 (vasoactive intestinal peptide receptor 2, n = 7), Scl17a8 -Cre/Ai9 (VGLUT3, vesicular glutamate transporter 3, n = 6), Gnb4 -Cre/Ai9 ( n = 1), and Slc17a8 -iCre/Ai9 ( n = 2) mice.", "title": null, "journal": "Nature", "cite_key": "Scala2021", "evidence": "Phenotypic variation of transcriptomic cell types in mouse motor cortex", "effect_size": null, "text_access": "fulltext", "study_system": "mouse M1", "_source_cluster": "cluster_06_disinhibition_circuit", "snowball_origin": "forward", "replication_status": "replication_unknown", "_source_cluster_index": 75, "claim_source_sentence": "2a ) were performed on wild-type C57Bl/6 ( n = 27), Viaat -Cre/Ai9 (vesicular inhibitory amino acid transporter, encoded by the Slc32a1 gene, n = 24), Sst -Cre/Ai9 (somatostatin, n = 75), Vip -Cre/Ai9 (vasoactive intestinal polypeptide, n = 46), Pvalb -Cre/Ai9 (parvalbumin, n = 76), Npy -Cre/Ai9 (neuropeptide Y, n = 2), Vipr2 -Cre/Ai9 (vasoactive intestinal peptide receptor 2, n = 7), Scl17a8 -Cre/Ai9 (VGLUT3, vesicular glutamate transporter 3, n = 6), Gnb4 -Cre/Ai9 ( n = 1), and Slc17a8 -iCre/Ai9 ( n = 2) mice.", "replication_evidence_dois": [], "effect_size_source_sentence": "Total number of neurons, 1,187 (for some cells soma depth could not be measured owing to failed staining). c , t-SNE representation of CGE-derived interneurons from the single-cell 10x v2 reference data set ( n = 15,511; perplexity, 30). t-Type names are shortened by omitting the first word; some are abbreviated." }, "section_id": "section_12", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-12-computational-models", "source_kind": "review_finding", "source_path": "evidence/section_12_evidence_package.json", "source_refs": [ "paper:paper-be132b319290" ], "source_span": "2a ) were performed on wild-type C57Bl/6 ( n = 27), Viaat -Cre/Ai9 (vesicular inhibitory amino acid transporter, encoded by the Slc32a1 gene, n = 24), Sst -Cre/Ai9 (somatostatin, n = 75), Vip -Cre/Ai9 (vasoactive intestinal polypeptide, n = 46), Pvalb -Cre/Ai9 (parvalbumin, n = 76), Npy -Cre/Ai9 (neuropeptide Y, n = 2), Vipr2 -Cre/Ai9 (vasoactive intestinal peptide receptor 2, n = 7), Scl17a8 -Cre/Ai9 (VGLUT3, vesic...", "study_system": "mouse M1", "evidence_refs": [ { "ref": "paper:paper-be132b319290" } ], "section_title": "Computational Models of VIP Circuit Function", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Phenotypic variation of transcriptomic cell types in mouse motor cortex", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-12-computational-models", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }