Details

scope
mouse M1
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-12-computational-models
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
study_system
mouse M1
section_title
Computational Models of VIP Circuit Function
evidence_summary
Phenotypic variation of transcriptomic cell types in mouse motor cortex
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-12-computational-models
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
claim_text
2a ) were performed on wild-type C57Bl/6 ( n = 27), Viaat -Cre/Ai9 (vesicular inhibitory amino acid transporter, encoded by the Slc32a1 gene, n = 24), Sst -Cre/Ai9 (somatostatin, n = 75), Vip -Cre/Ai9 (vasoactive intestinal polypeptide, n = 46), Pvalb -Cre/Ai9 (parvalbumin, n = 76), Npy -Cre/Ai9 (neuropeptide Y, n = 2), Vipr2 -Cre/Ai9 (vasoactive intestinal peptide receptor 2, n = 7), Scl17a8 -Cre/Ai9 (VGLUT3, vesicular glutamate transporter 3, n = 6), Gnb4 -Cre/Ai9 ( n = 1), and Slc17a8 -iCre/Ai9 ( n = 2) mice.
raw_fields
{
  "n": 27,
  "doi": "10.1038/s41586-020-2907-3",
  "year": "2020",
  "claim": "2a ) were performed on wild-type C57Bl/6 ( n = 27), Viaat -Cre/Ai9 (vesicular inhibitory amino acid transporter, encoded by the Slc32a1 gene, n = 24), Sst -Cre/Ai9 (somatostatin, n = 75), Vip -Cre/Ai9 (vasoactive intestinal polypeptide, n = 46), Pvalb -Cre/Ai9 (parvalbumin, n = 76), Npy -Cre/Ai9 (neuropeptide Y, n = 2), Vipr2 -Cre/Ai9 (vasoactive intestinal peptide receptor 2, n = 7), Scl17a8 -Cre/Ai9 (VGLUT3, vesicular glutamate transporter 3, n = 6), Gnb4 -Cre/Ai9 ( n = 1), and Slc17a8 -iCre/Ai9 ( n = 2) mice.",
  "title": null,
  "journal": "Nature",
  "cite_key": "Scala2021",
  "evidence": "Phenotypic variation of transcriptomic cell types in mouse motor cortex",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse M1",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "snowball_origin": "forward",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 75,
  "claim_source_sentence": "2a ) were performed on wild-type C57Bl/6 ( n = 27), Viaat -Cre/Ai9 (vesicular inhibitory amino acid transporter, encoded by the Slc32a1 gene, n = 24), Sst -Cre/Ai9 (somatostatin, n = 75), Vip -Cre/Ai9 (vasoactive intestinal polypeptide, n = 46), Pvalb -Cre/Ai9 (parvalbumin, n = 76), Npy -Cre/Ai9 (neuropeptide Y, n = 2), Vipr2 -Cre/Ai9 (vasoactive intestinal peptide receptor 2, n = 7), Scl17a8 -Cre/Ai9 (VGLUT3, vesicular glutamate transporter 3, n = 6), Gnb4 -Cre/Ai9 ( n = 1), and Slc17a8 -iCre/Ai9 ( n = 2) mice.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Total number of neurons, 1,187 (for some cells soma depth could not be measured owing to failed staining). c , t-SNE representation of CGE-derived interneurons from the single-cell 10x v2 reference data set ( n = 15,511; perplexity, 30). t-Type names are shortened by omitting the first word; some are abbreviated."
}
source_refs
[
  "paper:paper-be132b319290"
]
source_span
2a ) were performed on wild-type C57Bl/6 ( n = 27), Viaat -Cre/Ai9 (vesicular inhibitory amino acid transporter, encoded by the Slc32a1 gene, n = 24), Sst -Cre/Ai9 (somatostatin, n = 75), Vip -Cre/Ai9 (vasoactive intestinal polypeptide, n = 46), Pvalb -Cre/Ai9 (parvalbumin, n = 76), Npy -Cre/Ai9 (neuropeptide Y, n = 2), Vipr2 -Cre/Ai9 (vasoactive intestinal peptide receptor 2, n = 7), Scl17a8 -Cre/Ai9 (VGLUT3, vesic...
evidence_refs
[
  {
    "ref": "paper:paper-be132b319290"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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