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- Live5/17/2026, 4:35:28 PM
446040359af8Content snapshot
{ "scope": "anatomical classification basis for 3IN models", "claim_text": "Three-group classification analysis of GABAergic interneurons (parvalbumin, somatostatin, calretinin/VIP) provides quantitative basis for computational models with three interneuron classes.", "raw_fields": { "n": null, "id": "cluster_11_finding_117", "doi": "10.1002/dneu.20853", "pmid": "21154909", "year": "2011", "claim": "Three-group classification analysis of GABAergic interneurons (parvalbumin, somatostatin, calretinin/VIP) provides quantitative basis for computational models with three interneuron classes.", "pmcid": "PMC3556905", "title": "Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons.", "authors": "Rudy B, Fishell G, Lee S, Hjerling-Leffler J.", "journal": "Developmental neurobiology", "cite_key": "Rudy2011", "evidence": "Classification of cortical interneurons into three molecular/functional groups; foundational for 3IN models.", "effect_size": null, "text_access": "abstract_only", "study_system": "anatomical classification basis for 3IN models", "_source_cluster": "cluster_11_computational_models", "replication_status": "single_study", "_source_cluster_index": 116, "claim_source_sentence": "Recent data suggest that neurons expressing three markers, the Ca2+-binding protein parvalbumin (PV), the neuropeptide somatostatin (SST), and the ionotropic serotonin receptor 5HT3a (5HT3aR) account for nearly 100% of neocortical interneurons.", "replication_evidence_dois": [], "effect_size_source_sentence": null }, "section_id": "section_12", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-12-computational-models", "source_kind": "review_finding", "source_path": "evidence/section_12_evidence_package.json", "source_refs": [ "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9" ], "source_span": "Recent data suggest that neurons expressing three markers, the Ca2+-binding protein parvalbumin (PV), the neuropeptide somatostatin (SST), and the ionotropic serotonin receptor 5HT3a (5HT3aR) account for nearly 100% of neocortical interneurons.", "study_system": "anatomical classification basis for 3IN models", "evidence_refs": [ { "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9" } ], "section_title": "Computational Models of VIP Circuit Function", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Classification of cortical interneurons into three molecular/functional groups; foundational for 3IN models.", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "single_study", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-12-computational-models", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }