Details

scope
anatomical classification basis for 3IN models
claim_text
Three-group classification analysis of GABAergic interneurons (parvalbumin, somatostatin, calretinin/VIP) provides quantitative basis for computational models with three interneuron classes.
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-12-computational-models
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
study_system
anatomical classification basis for 3IN models
section_title
Computational Models of VIP Circuit Function
evidence_summary
Classification of cortical interneurons into three molecular/functional groups; foundational for 3IN models.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
single_study
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-12-computational-models
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
raw_fields
{
  "n": null,
  "id": "cluster_11_finding_117",
  "doi": "10.1002/dneu.20853",
  "pmid": "21154909",
  "year": "2011",
  "claim": "Three-group classification analysis of GABAergic interneurons (parvalbumin, somatostatin, calretinin/VIP) provides quantitative basis for computational models with three interneuron classes.",
  "pmcid": "PMC3556905",
  "title": "Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons.",
  "authors": "Rudy B, Fishell G, Lee S, Hjerling-Leffler J.",
  "journal": "Developmental neurobiology",
  "cite_key": "Rudy2011",
  "evidence": "Classification of cortical interneurons into three molecular/functional groups; foundational for 3IN models.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "anatomical classification basis for 3IN models",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "single_study",
  "_source_cluster_index": 116,
  "claim_source_sentence": "Recent data suggest that neurons expressing three markers, the Ca2+-binding protein parvalbumin (PV), the neuropeptide somatostatin (SST), and the ionotropic serotonin receptor 5HT3a (5HT3aR) account for nearly 100% of neocortical interneurons.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
]
source_span
Recent data suggest that neurons expressing three markers, the Ca2+-binding protein parvalbumin (PV), the neuropeptide somatostatin (SST), and the ionotropic serotonin receptor 5HT3a (5HT3aR) account for nearly 100% of neocortical interneurons.
evidence_refs
[
  {
    "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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