In mouse anterolateral motor cortex, thalamocortical inputs from VM thalamus se…

{
  "n": 0,
  "doi": "10.1523/jneurosci.1333-18.2018",
  "claim": "In mouse anterolateral motor cortex, thalamocortical inputs from VM thalamus selectively excite L5B PT neurons (via apical tuft synapses in L1) and L2/3 excitatory neurons but not L6 CT neurons, defining cell-type-specific E→E targeting.",
  "cite_key": "Guo2018",
  "evidence": "Channelrhodopsin-assisted circuit mapping and electrophysiology from retrogradely labeled PT, CT, and L2/3 neurons in mouse ALM.",
  "effect_size": "qualitative selectivity: VM→PT and VM→L2/3 strong vs VM→CT absent",
  "text_access": "abstract_only",
  "study_system": "mouse anterolateral motor cortex (ALM), male and female",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "In cortex, thalamocortical (TC) axons from VM thalamus excited VM-projecting pyramidal tract (PT) neurons in layer 5B of ALM. These axons also strongly excited layer 2/3 neurons (which strongly excite PT neurons, as previously shown) but not VM-projecting corticothalamic (CT) neurons in layer 6.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1523/JNEUROSCI.4023-14.2015",
    "10.1523/ENEURO.0154-24.2024"
  ],
  "effect_size_source_sentence": "The strongest connections in the VM → PT circuit were localized to apical tuft dendrites of PT neurons, in layer 1."
}

[
  "paper:e0b74a67-34de-4660-b780-ff95451e6841"
]

In cortex, thalamocortical (TC) axons from VM thalamus excited VM-projecting pyramidal tract (PT) neurons in layer 5B of ALM. These axons also strongly excited layer 2/3 neurons (which strongly excite PT neurons, as previously shown) but not VM-projecting corticothalamic (CT) neurons in layer 6.

[
  {
    "ref": "paper:e0b74a67-34de-4660-b780-ff95451e6841"
  }
]

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}