Version history

{
  "scope": "Mouse PFC; whole-brain single-neuron axon reconstruction.",
  "claim_text": "Single-neuron reconstruction of 6,357 mouse prefrontal cortex projection neurons identifies 64 projectome-defined subtypes that map onto four major cortico-cortical subnetworks targeted by distinct PFC subtypes defined by their first-order axon collaterals.",
  "raw_fields": {
    "n": 6357,
    "doi": "10.1038/s41593-022-01041-5",
    "claim": "Single-neuron reconstruction of 6,357 mouse prefrontal cortex projection neurons identifies 64 projectome-defined subtypes that map onto four major cortico-cortical subnetworks targeted by distinct PFC subtypes defined by their first-order axon collaterals.",
    "cite_key": "Gao2022",
    "evidence": "Sparse labelling + whole-brain imaging + single-neuron axon reconstruction of mouse PFC; hierarchical clustering by axon collateral targets.",
    "effect_size": "6,357 PFC projection neurons; 64 projectome subtypes; four major cortico-cortical subnetworks each targeted by a distinct group of subtypes.",
    "text_access": "abstract_only",
    "study_system": "Mouse PFC; whole-brain single-neuron axon reconstruction.",
    "argument_role": "supporting",
    "replication_status": "replicated",
    "claim_source_sentence": "Using single-neuron reconstruction of 6,357 mouse PFC projection neurons, we identified 64 projectome-defined subtypes.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1038/s41586-021-03941-1"
    ],
    "effect_size_source_sentence": "Each of four previously known major cortico-cortical subnetworks was targeted by a distinct group of PFC subtypes defined by their first-order axon collaterals."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "effect_size": "6,357 PFC projection neurons; 64 projectome subtypes; four major cortico-cortical subnetworks each targeted by a distinct group of subtypes.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-d2a88b47c74f"
  ],
  "source_span": "Using single-neuron reconstruction of 6,357 mouse PFC projection neurons, we identified 64 projectome-defined subtypes.",
  "study_system": "Mouse PFC; whole-brain single-neuron axon reconstruction.",
  "evidence_refs": [
    {
      "ref": "paper:paper-d2a88b47c74f"
    }
  ],
  "section_title": "8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Sparse labelling + whole-brain imaging + single-neuron axon reconstruction of mouse PFC; hierarchical clustering by axon collateral targets.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}