Details
- scope
- mouse primary somatosensory and motor cortex; optogenetic + whole-cell recordings of long-range corticocortical synapses
- claim_text
- Long-range corticocortical excitatory inputs between mouse S1 and M1 show strong synaptic facilitation, in contrast to the depression seen at local intracortical and thalamocortical inputs.
- section_id
- section_05
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
- effect_size
- Pronounced short-term facilitation at S1↔M1 synapses; depression at local/intracortical synapses
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-05-horizontal
- source_kind
- review_finding
- source_path
- evidence/section_05_evidence_package.json
- source_span
- We found that short-term facilitation was strong in both corticocortical synapses, resulting in far more sustained responses than local intracortical and thalamocortical connections.
- study_system
- mouse primary somatosensory and motor cortex; optogenetic + whole-cell recordings of long-range corticocortical synapses
- section_title
- 5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay
- evidence_summary
- Optogenetic activation of long-range S1↔M1 axons paired with whole-cell recordings of identified postsynaptic neurons in mouse cortical slices.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- single_study
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-05-horizontal
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1093/cercor/bhab325", "claim": "Long-range corticocortical excitatory inputs between mouse S1 and M1 show strong synaptic facilitation, in contrast to the depression seen at local intracortical and thalamocortical inputs.", "cite_key": "Martinetti2022", "evidence": "Optogenetic activation of long-range S1↔M1 axons paired with whole-cell recordings of identified postsynaptic neurons in mouse cortical slices.", "effect_size": "Pronounced short-term facilitation at S1↔M1 synapses; depression at local/intracortical synapses", "text_access": "abstract_only", "study_system": "mouse primary somatosensory and motor cortex; optogenetic + whole-cell recordings of long-range corticocortical synapses", "argument_role": "supporting", "replication_status": "single_study", "claim_source_sentence": "We found that short-term facilitation was strong in both corticocortical synapses, resulting in far more sustained responses than local intracortical and thalamocortical connections.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "A major difference between pathways was that the synaptic strength and magnitude of facilitation were distinct for individual excitatory cells located across all cortical layers and specific subtypes of GABAergic neurons." }- source_refs
[ "paper:paper-588744b42344" ]
- evidence_refs
[ { "ref": "paper:paper-588744b42344" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }