Horizontal long-range intracortical excitatory connections in mouse cortex
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1CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
2CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
3CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
4CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
5CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
7CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
8CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
9CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
10CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
2CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference0 The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
2CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference1 The translaminar loops surveyed in{ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted “patches” that selectively c... -
2CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference2 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 2CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference3; the... -
2CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference4 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 2CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference5; the... -
2CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference6 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 2CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference7; the... -
2CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference8 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 2CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference9; the... -
3CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference0 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 3CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference1; the... -
3CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference2 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 3CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference3; the... -
3CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference4 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 3CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference5; the... -
3CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference6 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 3CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference7; the... -
3CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference8 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 3CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference9; the... -
4CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference0 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 4CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference1; the... -
4CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference2 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 4CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference3; the... -
4CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference4 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 4CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference5; the... -
4CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference6 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 4CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference7; the... -
4CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference8 Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet 4CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference9; the... -
5CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference0 The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions 5CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference1, an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr... -
5CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference2 The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions 5CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference3, an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr... -
5CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference4 The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions 5CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference5, an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr... -
5CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference6 The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions 5CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference7, an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr... -
5CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference8 The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions 5CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference9, an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference0 The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions 6CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference1, an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference2 The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading.{numref}fig-sec05-distance-extentmakes this explicit. Local in vivo paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference3 The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading.{numref}fig-sec05-distance-extentmakes this explicit. Local in vivo paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference4 The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading.{numref}fig-sec05-distance-extentmakes this explicit. Local in vivo paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference5 The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading.{numref}fig-sec05-distance-extentmakes this explicit. Local in vivo paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference6 The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading.{numref}fig-sec05-distance-extentmakes this explicit. Local in vivo paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference7 The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading.{numref}fig-sec05-distance-extentmakes this explicit. Local in vivo paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference8 The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading.{numref}fig-sec05-distance-extentmakes this explicit. Local in vivo paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con... -
6CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference9 The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading.{numref}fig-sec05-distance-extentmakes this explicit. Local in vivo paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con... -
7CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference0 Spatial extent of intracortical E→E connectivity in mouse cortex. Three independent panels report three different spatial observables: a local in vivo pyramidal–pyramidal P(connection) of 6.7% in mouse S1 L2 (panel A, 7CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference1), an ensemble net-activation radius of ~30 µm with suppression beyond, measured by all-optical interrogation in awake mouse V1 L2/3 (panel B, 7CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference2), and a qualitative... -
7CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference3 Spatial extent of intracortical E→E connectivity in mouse cortex. Three independent panels report three different spatial observables: a local in vivo pyramidal–pyramidal P(connection) of 6.7% in mouse S1 L2 (panel A, 7CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference4), an ensemble net-activation radius of ~30 µm with suppression beyond, measured by all-optical interrogation in awake mouse V1 L2/3 (panel B, 7CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference5), and a qualitative... -
7CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference6 Spatial extent of intracortical E→E connectivity in mouse cortex. Three independent panels report three different spatial observables: a local in vivo pyramidal–pyramidal P(connection) of 6.7% in mouse S1 L2 (panel A, 7CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference7), an ensemble net-activation radius of ~30 µm with suppression beyond, measured by all-optical interrogation in awake mouse V1 L2/3 (panel B, 7CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference8), and a qualitative... -
7CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference9 Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer 8CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference0, and the L2/3 connection probabilities measured in vitro by this study are substantially higher than the same nominal population sampled in vivo by... -
8CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference1 Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer 8CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference2, and the L2/3 connection probabilities measured in vitro by this study are substantially higher than the same nominal population sampled in vivo by... -
8CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference3 Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer 8CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference4, and the L2/3 connection probabilities measured in vitro by this study are substantially higher than the same nominal population sampled in vivo by... -
8CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference5 Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer 8CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference6, and the L2/3 connection probabilities measured in vitro by this study are substantially higher than the same nominal population sampled in vivo by... -
8CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference7 Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer 8CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference8, and the L2/3 connection probabilities measured in vitro by this study are substantially higher than the same nominal population sampled in vivo by... -
8CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference9 Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer 9CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference0, and the L2/3 connection probabilities measured in vitro by this study are substantially higher than the same nominal population sampled in vivo by... -
9CitationThe translaminar loops surveyed in {ref}
sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference1 Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer 9CitationThe translaminar loops surveyed in {ref}sec-translaminarclose the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...content/05_horizontal.md:line 5Open reference2, and the L2/3 connection probabilities measured in vitro by this study are substantially higher than the same nominal population sampled in vivo by... -
... 109 additional anchors in refs_json
References
- [Winnubst2019] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Liu2022b] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Ko2011] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Cossell2015] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Lee2016] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Lefort2009] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Watkins2014] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Ding2025] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [TheMICrONSConsortium2025] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Liu2025a] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Hansel2012] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [Pattadkal2018] “The translaminar loops surveyed in {ref}`sec-translaminar` close the cortical column: L4 drives L2/3, L2/3 drives L5 and L6, and L5/L6 return both intracolumnar and subcortical output. The column is not, however, an electrically isolated unit. Each L2/3 and L5 pyramidal cell extends a tangential axonal arbor that traverses several millimetres of cortex, breaking into spatially restricted "patches" that selectively c...”
- [MunozCastaneda2021] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Whitesell2021] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Yao2024] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Chen2019a] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Mohan2023] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Petreanu2007] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Petreanu2009] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Bureau2006] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Kinnischtzke2016] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Martinetti2022] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Im2022] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Honnuraiah2026] “Single-cell reconstructions across V1, S1, and the motor areas make horizontal patchiness a defining feature of mouse pyramidal axons rather than a phenomenon of large primate cortex. Whole-brain reconstructions of more than a thousand projection neurons resolve cortical projection-neuron subtypes whose intra-areal axon collaterals are organised into discrete clusters rather than a uniform sheet [Winnubst2019]; the...”
- [Smith2010] “The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions [Smith2010], an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr...”
- [Bopp2014] “The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions [Smith2010], an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr...”
- [Brown2021] “The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions [Smith2010], an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr...”
- [Burkhalter2024] “The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions [Smith2010], an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr...”
- [Meier2025] “The morphology of those patches is consequential for downstream physiology. In mouse V1 L2/3, two-photon mapping of ON/OFF receptive-field subregions shows that neighbouring neurons frequently share whole subregions [Smith2010], an observation later used to anchor the idea that fine receptive fields tile cortex with the spacing of horizontal axon patches. Superficial pyramidal cells additionally form a far higher pr...”
- [Jouhanneau2015] “The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading. {numref}`fig-sec05-distance-extent` makes this explicit. Local *in vivo* paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con...”
- [Avermann2012] “The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading. {numref}`fig-sec05-distance-extent` makes this explicit. Local *in vivo* paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con...”
- [Lefort2017] “The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading. {numref}`fig-sec05-distance-extent` makes this explicit. Local *in vivo* paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con...”
- [Oldenburg2024] “The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading. {numref}`fig-sec05-distance-extent` makes this explicit. Local *in vivo* paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con...”
- [Hage2022] “The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading. {numref}`fig-sec05-distance-extent` makes this explicit. Local *in vivo* paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con...”
- [Seeman2018] “The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading. {numref}`fig-sec05-distance-extent` makes this explicit. Local *in vivo* paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con...”
- [Chau2025] “The number that one wants in this part of the inventory — the connection-probability-vs-distance curve for excitatory pairs — exists in the literature, but several incommensurable versions of it exist, and combining them into a single envelope is misleading. {numref}`fig-sec05-distance-extent` makes this explicit. Local *in vivo* paired recordings in mouse S1 barrel cortex L2 report only 6.7% pyramidal-pyramidal con...”
- [Campagnola2021] “Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer [Lefort2009], and the L2/3 connection probabilities measured *in vitro* by this study are substantially higher than the same nominal population sampled *in vivo* by...”
- [Chou2025] “Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer [Lefort2009], and the L2/3 connection probabilities measured *in vitro* by this study are substantially higher than the same nominal population sampled *in vivo* by...”
- [Chettih2019] “Paired recordings across the C2 barrel column anchored a more layer-resolved version of this for S1: the strongest excitatory drive on the column comes from presynaptic L4, with rare large-amplitude pyramidal-pyramidal connections detected in every layer [Lefort2009], and the L2/3 connection probabilities measured *in vitro* by this study are substantially higher than the same nominal population sampled *in vivo* by...”
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