Version history

{
  "scope": "Mouse acute slice; whole-cell recording from HVAs with optogenetic V1-axon activation.",
  "claim_text": "Whole-cell recordings combined with optogenetic stimulation of V1 axons in vitro reveal area-specific differences in the strength with which feedforward V1 inputs and within-area recurrent pathways recruit interneurons across mouse higher visual areas LM, AL, PM and AM.",
  "raw_fields": {
    "n": 4,
    "doi": "10.1016/j.cub.2021.09.042",
    "claim": "Whole-cell recordings combined with optogenetic stimulation of V1 axons in vitro reveal area-specific differences in the strength with which feedforward V1 inputs and within-area recurrent pathways recruit interneurons across mouse higher visual areas LM, AL, PM and AM.",
    "cite_key": "Li2021a",
    "evidence": "In-vitro whole-cell recordings from neurons in HVAs (LM, AL, PM, AM) of mouse cortex with optogenetic activation of V1 axons in slice.",
    "effect_size": "HVA-specific differences in V1-driven excitatory and inhibitory recruitment across LM, AL, PM, AM.",
    "text_access": "fulltext",
    "study_system": "Mouse acute slice; whole-cell recording from HVAs with optogenetic V1-axon activation.",
    "argument_role": "supporting",
    "replication_status": "replicated",
    "claim_source_sentence": "We discovered area-specific differences in the strength of recruitment of interneurons through feedforward and recurrent pathways, as well as differences in cell-class-specific recruitment.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [
      "10.1038/s41586-019-1716-z"
    ],
    "effect_size_source_sentence": "Here, we sought to determine whether higher order visual cortical areas lateromedial (LM), anterolateral (AL), posteromedial (PM), and anteromedial (AM) have specialized anatomical and physiological properties."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "effect_size": "HVA-specific differences in V1-driven excitatory and inhibitory recruitment across LM, AL, PM, AM.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-21937e5a070f"
  ],
  "source_span": "We discovered area-specific differences in the strength of recruitment of interneurons through feedforward and recurrent pathways, as well as differences in cell-class-specific recruitment.",
  "study_system": "Mouse acute slice; whole-cell recording from HVAs with optogenetic V1-axon activation.",
  "evidence_refs": [
    {
      "ref": "paper:paper-21937e5a070f"
    }
  ],
  "section_title": "8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "In-vitro whole-cell recordings from neurons in HVAs (LM, AL, PM, AM) of mouse cortex with optogenetic activation of V1 axons in slice.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}