Version history

{
  "scope": "rat frontal cortex L5 pyramidal cells (physiological subtypes)",
  "claim_text": "In rat frontal cortex L5, paired recordings revealed that L5 pyramidal cells of the same firing-pattern subtype shared more common L2/3 inputs and were preferentially synaptically connected to each other, establishing firing-pattern (projection-correlated) excitatory feed-forward subnetworks.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1523/jneurosci.1921-08.2008",
    "claim": "In rat frontal cortex L5, paired recordings revealed that L5 pyramidal cells of the same firing-pattern subtype shared more common L2/3 inputs and were preferentially synaptically connected to each other, establishing firing-pattern (projection-correlated) excitatory feed-forward subnetworks.",
    "cite_key": "Otsuka2008",
    "evidence": "Focal glutamate-uncaging stimulation of L2/3 with dual whole-cell recordings of physiologically classified L5 pyramidal cells in rat frontal cortex slices.",
    "effect_size": "qualitative — same-firing-pattern L5 pairs share more L2/3 inputs and connect more often",
    "text_access": "abstract_only",
    "study_system": "rat frontal cortex L5 pyramidal cells (physiological subtypes)",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "Dual recordings from L5 pyramidal cells revealed that common input probability that two L5 cells share inputs from a L2/3 cell was high in cell pairs of the same subtypes, compared with those in different subtype pairs.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1523/JNEUROSCI.0772-11.2011",
      "10.1523/JNEUROSCI.2810-11.2012"
    ],
    "effect_size_source_sentence": "Furthermore, the common input probability was highly selective when cell pairs of the same subtypes, but not different subtypes, had connections between them."
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "effect_size": "qualitative — same-firing-pattern L5 pairs share more L2/3 inputs and connect more often",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-c47fe4083db3"
  ],
  "source_span": "Dual recordings from L5 pyramidal cells revealed that common input probability that two L5 cells share inputs from a L2/3 cell was high in cell pairs of the same subtypes, compared with those in different subtype pairs.",
  "study_system": "rat frontal cortex L5 pyramidal cells (physiological subtypes)",
  "evidence_refs": [
    {
      "ref": "paper:paper-c47fe4083db3"
    }
  ],
  "section_title": "7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Focal glutamate-uncaging stimulation of L2/3 with dual whole-cell recordings of physiologically classified L5 pyramidal cells in rat frontal cortex slices.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}