In rat frontal cortex L5, paired recordings revealed that L5 pyramidal cells of…

In rat frontal cortex L5, paired recordings revealed that L5 pyramidal cells of the same firing-pattern subtype shared more common L2/3 inputs and were preferentially synaptically connected to each other, establishing firing-pattern (projection-correlated) excitatory feed-forward subnetworks.

{
  "n": 0,
  "doi": "10.1523/jneurosci.1921-08.2008",
  "claim": "In rat frontal cortex L5, paired recordings revealed that L5 pyramidal cells of the same firing-pattern subtype shared more common L2/3 inputs and were preferentially synaptically connected to each other, establishing firing-pattern (projection-correlated) excitatory feed-forward subnetworks.",
  "cite_key": "Otsuka2008",
  "evidence": "Focal glutamate-uncaging stimulation of L2/3 with dual whole-cell recordings of physiologically classified L5 pyramidal cells in rat frontal cortex slices.",
  "effect_size": "qualitative — same-firing-pattern L5 pairs share more L2/3 inputs and connect more often",
  "text_access": "abstract_only",
  "study_system": "rat frontal cortex L5 pyramidal cells (physiological subtypes)",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Dual recordings from L5 pyramidal cells revealed that common input probability that two L5 cells share inputs from a L2/3 cell was high in cell pairs of the same subtypes, compared with those in different subtype pairs.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1523/JNEUROSCI.0772-11.2011",
    "10.1523/JNEUROSCI.2810-11.2012"
  ],
  "effect_size_source_sentence": "Furthermore, the common input probability was highly selective when cell pairs of the same subtypes, but not different subtypes, had connections between them."
}

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