Version history

{
  "scope": "review of mouse cortical interneuron taxonomy",
  "claim_text": "PV-, SST- and 5HT3aR-expressing cortical interneurons together account for nearly 100% of GABAergic neurons in mouse somatosensory cortex, with the 5HT3aR group (which contains all VIP+ cells plus VIP-negative L1/Lamp5 cells) forming the third major group whose intrinsic electrophysiology is the most heterogeneous.",
  "raw_fields": {
    "n": null,
    "doi": "10.1002/dneu.20853",
    "claim": "PV-, SST- and 5HT3aR-expressing cortical interneurons together account for nearly 100% of GABAergic neurons in mouse somatosensory cortex, with the 5HT3aR group (which contains all VIP+ cells plus VIP-negative L1/Lamp5 cells) forming the third major group whose intrinsic electrophysiology is the most heterogeneous.",
    "title": null,
    "cite_key": "Rudy2011",
    "evidence": "review compiling 5HT3aR-BAC EGFP genetic targeting + scRT-PCR/IHC overlap data in mouse S1",
    "effect_size": "PV + SST + 5HT3aR ≈ 100% of cortical GABAergic INs (S1)",
    "text_access": "fulltext",
    "study_system": "review of mouse cortical interneuron taxonomy",
    "_source_cluster": "cluster_04_intrinsic_electrophysiology",
    "replication_status": "replicated",
    "_source_cluster_index": 45,
    "claim_source_sentence": "This analysis has provided strong evidence that three major groups of neurons, those expressing the Ca 2+ -binding protein parvalbumin (PV), those expressing the neuropeptide somatostatin (SST), and those expressing 5HT3aRs account for nearly 100% of GABAergic neurons in somatose...",
    "replication_evidence_dois": [
      "10.1523/jneurosci.1869-10.2010"
    ],
    "effect_size_source_sentence": "three major groups of neurons, those expressing the Ca 2+ -binding protein parvalbumin (PV), those expressing the neuropeptide somatostatin (SST), and those expressing 5HT3aRs account for nearly 100% of GABAergic neurons in somatosensory cortex."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "effect_size": "PV + SST + 5HT3aR ≈ 100% of cortical GABAergic INs (S1)",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
  ],
  "source_span": "This analysis has provided strong evidence that three major groups of neurons, those expressing the Ca 2+ -binding protein parvalbumin (PV), those expressing the neuropeptide somatostatin (SST), and those expressing 5HT3aRs account for nearly 100% of GABAergic neurons in somatose...",
  "study_system": "review of mouse cortical interneuron taxonomy",
  "evidence_refs": [
    {
      "ref": "paper:34a07597-2d6f-4552-b9cf-d2d11817f9f9"
    }
  ],
  "section_title": "Intrinsic Electrophysiology",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "review compiling 5HT3aR-BAC EGFP genetic targeting + scRT-PCR/IHC overlap data in mouse S1",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}