Details
- scope
- mouse V1 L2/3, Wfs1-Cre transgenic line, two-photon calcium imaging
- claim_text
- Wfs1-Cre labels a layer 2/3 excitatory cell population in mouse V1, providing a genetic handle for in vivo two-photon imaging of L2/3 IT-class pyramidal neurons with sharp orientation, direction and spatial-frequency tuning.
- section_id
- section_02
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-02-anatomy-primer
- source_kind
- review_finding
- source_path
- evidence/section_02_evidence_package.json
- study_system
- mouse V1 L2/3, Wfs1-Cre transgenic line, two-photon calcium imaging
- section_title
- 2. Mouse-cortex anatomy primer — areal map, layer structure, projection-class nomenclature (IT / PT / CT), tools available for E→E dissection (paired patch, Cre lines, two-photon-targeted patch, optogenetics, EM reconstruction)
- evidence_summary
- Two-photon calcium imaging in Wfs1-Cre × tdTomato reporter mice expressing GCaMP/dye in L2/3 of V1.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-02-anatomy-primer
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- raw_fields
{ "n": null, "doi": "10.3389/fnsys.2010.00162", "claim": "Wfs1-Cre labels a layer 2/3 excitatory cell population in mouse V1, providing a genetic handle for in vivo two-photon imaging of L2/3 IT-class pyramidal neurons with sharp orientation, direction and spatial-frequency tuning.", "cite_key": "Zariwala2011", "evidence": "Two-photon calcium imaging in Wfs1-Cre × tdTomato reporter mice expressing GCaMP/dye in L2/3 of V1.", "effect_size": null, "text_access": "abstract_only", "study_system": "mouse V1 L2/3, Wfs1-Cre transgenic line, two-photon calcium imaging", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Wfs1(+)/Gad1(-) mice that labels layer 2/3 excitatory cell population... We found that the Wfs1(+) cells exhibited visual tuning properties comparable to the excitatory population, i.e., high selectivity and tuning to the angle, direction, and spatial frequency of oriented moving gratings.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-pm-21283555" ]
- source_span
Wfs1(+)/Gad1(-) mice that labels layer 2/3 excitatory cell population... We found that the Wfs1(+) cells exhibited visual tuning properties comparable to the excitatory population, i.e., high selectivity and tuning to the angle, direction, and spatial frequency of oriented moving gratings.
- evidence_refs
[ { "ref": "paper:paper-pm-21283555" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }