We found that the intrinsic and synaptic properties of VIP+ interneurons and py…

Details

scope: mouse neocortex
claim_text: We found that the intrinsic and synaptic properties of VIP+ interneurons and pyramidal neurons were concordantly affected prior to a progressive loss of VIP+ interneurons.
section_id: section_07
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
review_repo: ComputationalReviewVIP
section_ref: wiki_page:computationalreviewvip-07-disinhibition-framework
source_kind: review_finding
source_path: evidence/section_07_evidence_package.json
source_span: We found that the intrinsic and synaptic properties of VIP+ interneurons and pyramidal neurons were concordantly affected prior to a progressive loss of VIP+ interneurons.
study_system: mouse neocortex
section_title: Local Circuit Motifs and the Disinhibition Framework
evidence_summary: microRNA Deficiency in VIP+ Interneurons Leads to Cortical Circuit Dysfunction
review_bundle_ref: analysis_bundle:ab-2ce40c33e827
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-2ce40c33e827
source_artifact_ref: wiki_page:computationalreviewvip-07-disinhibition-framework
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
commit_sha: 95e761177f7d2ec565983d3307c14ec238f9677c
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP

Raw fields (4)

raw_fields

{
  "n": null,
  "doi": "10.1093/cercor/bhz236",
  "year": "2019",
  "claim": "We found that the intrinsic and synaptic properties of VIP+ interneurons and pyramidal neurons were concordantly affected prior to a progressive loss of VIP+ interneurons.",
  "title": null,
  "journal": "Cerebral cortex (New York, N.Y. : 1991)",
  "cite_key": "Qiu2020",
  "evidence": "microRNA Deficiency in VIP+ Interneurons Leads to Cortical Circuit Dysfunction",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse neocortex",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "snowball_origin": "backward_r2",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 96,
  "claim_source_sentence": "We found that the intrinsic and synaptic properties of VIP+ interneurons and pyramidal neurons were concordantly affected prior to a progressive loss of VIP+ interneurons.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-e09b4f7909d5"
]

evidence_refs

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  }
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source_policy

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We found that the intrinsic and synaptic properties of VIP+ interneurons and py…

Details

Replication

Discussion