Version history

{
  "scope": "mouse striatum slice, TH-Cre lines",
  "claim_text": "Striatal tyrosine hydroxylase-expressing interneurons accessed via TH-Cre lines do not co-release dopamine despite their TH expression, behaving as GABAergic interneurons.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1523/jneurosci.0195-15.2015",
    "claim": "Striatal tyrosine hydroxylase-expressing interneurons accessed via TH-Cre lines do not co-release dopamine despite their TH expression, behaving as GABAergic interneurons.",
    "cite_key": "Xenias2015",
    "evidence": "ChR2-assisted circuit mapping with TH-Cre lines and pharmacological tests for dopamine release.",
    "effect_size": "2 and",
    "text_access": "abstract_only",
    "study_system": "mouse striatum slice, TH-Cre lines",
    "source_cluster_id": "cluster_10",
    "replication_status": "contested",
    "claim_source_sentence": "Striatal GABAergic interneurons that express the gene for tyrosine hydroxylase (TH) have been identified previously by several methods.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "In TH-Cre mice whose nigrostriatal pathway had been eliminated unilaterally with 6-hydroxydopamine, we injected a Cre-dependent virus coding for channelrhodopsin-2 and enhanced yellow fluorescent protein unilaterally into the unlesioned midbrain or bilaterally into the striatum."
  },
  "section_id": "section_11",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json",
  "effect_size": "2 and",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-11",
  "source_kind": "review_finding",
  "source_path": "evidence/section_11_evidence_package.json",
  "source_refs": [
    "paper:paper-da9538ac0127"
  ],
  "source_span": "Striatal GABAergic interneurons that express the gene for tyrosine hydroxylase (TH) have been identified previously by several methods.",
  "study_system": "mouse striatum slice, TH-Cre lines",
  "evidence_refs": [
    {
      "ref": "paper:paper-da9538ac0127"
    }
  ],
  "section_title": "Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "ChR2-assisted circuit mapping with TH-Cre lines and pharmacological tests for dopamine release.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "contested",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-11",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}