Details
- scope
- mouse striatum slice, TH-Cre lines
- claim_text
- Striatal tyrosine hydroxylase-expressing interneurons accessed via TH-Cre lines do not co-release dopamine despite their TH expression, behaving as GABAergic interneurons.
- section_id
- section_11
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- effect_size
- 2 and
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-11
- source_kind
- review_finding
- source_path
- evidence/section_11_evidence_package.json
- source_span
- Striatal GABAergic interneurons that express the gene for tyrosine hydroxylase (TH) have been identified previously by several methods.
- study_system
- mouse striatum slice, TH-Cre lines
- section_title
- Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)
- evidence_summary
- ChR2-assisted circuit mapping with TH-Cre lines and pharmacological tests for dopamine release.
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- contested
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-11
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1523/jneurosci.0195-15.2015", "claim": "Striatal tyrosine hydroxylase-expressing interneurons accessed via TH-Cre lines do not co-release dopamine despite their TH expression, behaving as GABAergic interneurons.", "cite_key": "Xenias2015", "evidence": "ChR2-assisted circuit mapping with TH-Cre lines and pharmacological tests for dopamine release.", "effect_size": "2 and", "text_access": "abstract_only", "study_system": "mouse striatum slice, TH-Cre lines", "source_cluster_id": "cluster_10", "replication_status": "contested", "claim_source_sentence": "Striatal GABAergic interneurons that express the gene for tyrosine hydroxylase (TH) have been identified previously by several methods.", "replication_evidence_dois": [], "effect_size_source_sentence": "In TH-Cre mice whose nigrostriatal pathway had been eliminated unilaterally with 6-hydroxydopamine, we injected a Cre-dependent virus coding for channelrhodopsin-2 and enhanced yellow fluorescent protein unilaterally into the unlesioned midbrain or bilaterally into the striatum." }- source_refs
[ "paper:paper-da9538ac0127" ]
- evidence_refs
[ { "ref": "paper:paper-da9538ac0127" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }