Version history

{
  "scope": "Mouse cortex recurrent network models with PYR, PV, SST, VIP populations; theoretical and numerical analysis",
  "claim_text": "In four-population (PYR, PV, SST, VIP) network models, the paradoxical effect upon PV photo-excitation can occur even when the network is not inhibition-stabilized, complicating the inference of ISN regime from paradoxical responses.",
  "raw_fields": {
    "n": 0,
    "doi": "10.7554/elife.49967",
    "claim": "In four-population (PYR, PV, SST, VIP) network models, the paradoxical effect upon PV photo-excitation can occur even when the network is not inhibition-stabilized, complicating the inference of ISN regime from paradoxical responses.",
    "cite_key": "Mahrach2020",
    "evidence": "Mathematical analysis and simulations of mouse cortical four-population recurrent networks with PV, SST, VIP interneuron classes; comparison to two-population network theory.",
    "effect_size": "paradoxical effect in 4-pop network can occur outside ISN regime (qualitative, derived analytically)",
    "text_access": "fulltext",
    "study_system": "Mouse cortex recurrent network models with PYR, PV, SST, VIP populations; theoretical and numerical analysis",
    "argument_role": "supporting",
    "replication_status": "within_lab",
    "claim_source_sentence": "Here we show that in contrast, in four-population networks, the paradoxical effect can occur even if the network is not inhibition stabilized.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_09",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json",
  "effect_size": "paradoxical effect in 4-pop network can occur outside ISN regime (qualitative, derived analytically)",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-09-amplification-isn",
  "source_kind": "review_finding",
  "source_path": "evidence/section_09_evidence_package.json",
  "source_refs": [
    "paper:paper-38fe71bdf9b6"
  ],
  "source_span": "Here we show that in contrast, in four-population networks, the paradoxical effect can occur even if the network is not inhibition stabilized.",
  "study_system": "Mouse cortex recurrent network models with PYR, PV, SST, VIP populations; theoretical and numerical analysis",
  "evidence_refs": [
    {
      "ref": "paper:paper-38fe71bdf9b6"
    }
  ],
  "section_title": "9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Mathematical analysis and simulations of mouse cortical four-population recurrent networks with PV, SST, VIP interneuron classes; comparison to two-population network theory.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "within_lab",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-09-amplification-isn",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}