Details

scope
Mouse motor and auditory cortex; in situ sequencing barcode + multiplex gene panel
claim_text
BARseq2 simultaneously profiles single-cell projections and multiplexed gene expression in 29,933 cells and projections from 3,164 cells in mouse cortex.
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
effect_size
29,933 cells profiled; 3,164 cells projection-mapped; 1,349 with both
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-12
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
source_span
We determined the expression of cadherins and cell-type markers in 29,933 cells and the projections of 3,164 cells in both the mouse motor cortex and auditory cortex.
study_system
Mouse motor and auditory cortex; in situ sequencing barcode + multiplex gene panel
section_title
Whole-Brain Connectomics: Mouse, Primate, Human
evidence_summary
BARseq2 links transcriptomic identity to projection patterns at scale, addressing the molecular logic of single-neuron projections.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-12
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 29933,
  "doi": "10.1038/s41593-021-00842-4",
  "claim": "BARseq2 simultaneously profiles single-cell projections and multiplexed gene expression in 29,933 cells and projections from 3,164 cells in mouse cortex.",
  "cite_key": "Sun2021",
  "evidence": "BARseq2 links transcriptomic identity to projection patterns at scale, addressing the molecular logic of single-neuron projections.",
  "effect_size": "29,933 cells profiled; 3,164 cells projection-mapped; 1,349 with both",
  "text_access": "abstract_only",
  "study_system": "Mouse motor and auditory cortex; in situ sequencing barcode + multiplex gene panel",
  "source_cluster_id": "cluster_11",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "We determined the expression of cadherins and cell-type markers in 29,933 cells and the projections of 3,164 cells in both the mouse motor cortex and auditory cortex.",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2016.07.036",
    "10.1038/s41467-024-52756-x"
  ],
  "effect_size_source_sentence": "We determined the expression of cadherins and cell-type markers in 29,933 cells and the projections of 3,164 cells in both the mouse motor cortex and auditory cortex."
}
source_refs
[
  "paper:paper-533dcc333951"
]
evidence_refs
[
  {
    "ref": "paper:paper-533dcc333951"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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