Details

scope
male mouse auditory cortex (A1); LSPS + 2P imaging
section_id
section_04
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
effect_size
L2 > L3 columnar integration / bandwidth; L3 receives more L4 translaminar input.
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-04-translaminar
source_kind
review_finding
source_path
evidence/section_04_evidence_package.json
study_system
male mouse auditory cortex (A1); LSPS + 2P imaging
section_title
4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections
evidence_summary
Slice whole-cell recordings with laser-scanning photostimulation + in vivo 2P calcium imaging in mouse A1.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-04-translaminar
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (6)
claim_text
Sublaminar subdivisions exist within mouse auditory L2/3: superficial L2 cells show wider columnar (tonotopic) integration and higher bandwidth, while deeper L3 cells receive proportionally more L4 translaminar input and are more frequency-selective.
raw_fields
{
  "n": 0,
  "doi": "10.1523/jneurosci.1361-17.2017",
  "claim": "Sublaminar subdivisions exist within mouse auditory L2/3: superficial L2 cells show wider columnar (tonotopic) integration and higher bandwidth, while deeper L3 cells receive proportionally more L4 translaminar input and are more frequency-selective.",
  "cite_key": "Meng2017",
  "evidence": "Slice whole-cell recordings with laser-scanning photostimulation + in vivo 2P calcium imaging in mouse A1.",
  "effect_size": "L2 > L3 columnar integration / bandwidth; L3 receives more L4 translaminar input.",
  "text_access": "abstract_only",
  "study_system": "male mouse auditory cortex (A1); LSPS + 2P imaging",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Cells in superficial L2 show more extensive columnar integration than deeper L3 cells. Moreover, L3 cells receive more translaminar input from L4.imaging in awake mice revealed that L2 cells had higher bandwidth than L3 cells, consistent with the laminar differences in columnar integration.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-3c2ac9842638"
]
source_span
Cells in superficial L2 show more extensive columnar integration than deeper L3 cells. Moreover, L3 cells receive more translaminar input from L4.imaging in awake mice revealed that L2 cells had higher bandwidth than L3 cells, consistent with the laminar differences in columnar integration.
evidence_refs
[
  {
    "ref": "paper:paper-3c2ac9842638"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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