Version history

{
  "scope": "mouse barrel/somatosensory cortex, acute slices, ChR2-assisted circuit mapping (CRACM) of L2/3 axons onto L2/3, L4, L5, L6 targets in ipsilateral and contralateral cortex",
  "claim_text": "Callosal projections from mouse somatosensory cortex L2/3 axons connect with L5, L2/3 and L6 — but not L4 — in both ipsilateral and contralateral cortex, with the L2/3→L5 projection stronger than L2/3→L2/3.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/nn1891",
    "claim": "Callosal projections from mouse somatosensory cortex L2/3 axons connect with L5, L2/3 and L6 — but not L4 — in both ipsilateral and contralateral cortex, with the L2/3→L5 projection stronger than L2/3→L2/3.",
    "cite_key": "Petreanu2007",
    "evidence": "ChR2-assisted circuit mapping (CRACM) in mouse somatosensory cortex slices; ChR2 delivered to L2/3 pyramidal axons in vivo; photostimulation combined with whole-cell recording in ipsi- and contralateral hemisphere.",
    "effect_size": "L2/3→L5 stronger than L2/3→L2/3; L4 not contacted; quantitative input maps provided in figures.",
    "text_access": "abstract_only",
    "study_system": "mouse barrel/somatosensory cortex, acute slices, ChR2-assisted circuit mapping (CRACM) of L2/3 axons onto L2/3, L4, L5, L6 targets in ipsilateral and contralateral cortex",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "L2/3 axons connect with neurons in L5, L2/3 and L6, but not L4, in both ipsilateral and contralateral cortex. In both hemispheres the L2/3-to-L5 projection is stronger than the L2/3-to-L2/3 projection.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1038/nature07709",
      "10.1038/nature08935"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "L2/3→L5 stronger than L2/3→L2/3; L4 not contacted; quantitative input maps provided in figures.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:987379eb-ecdd-42eb-818f-383280a8fca9"
  ],
  "source_span": "L2/3 axons connect with neurons in L5, L2/3 and L6, but not L4, in both ipsilateral and contralateral cortex. In both hemispheres the L2/3-to-L5 projection is stronger than the L2/3-to-L2/3 projection.",
  "study_system": "mouse barrel/somatosensory cortex, acute slices, ChR2-assisted circuit mapping (CRACM) of L2/3 axons onto L2/3, L4, L5, L6 targets in ipsilateral and contralateral cortex",
  "evidence_refs": [
    {
      "ref": "paper:987379eb-ecdd-42eb-818f-383280a8fca9"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "ChR2-assisted circuit mapping (CRACM) in mouse somatosensory cortex slices; ChR2 delivered to L2/3 pyramidal axons in vivo; photostimulation combined with whole-cell recording in ipsi- and contralateral hemisphere.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}