Details

scope
rat frontal cortex layer 5, in vitro paired recordings
claim_text
In layer 5 frontal cortex, FS/PV cells make nonselective connections with both corticopontine and crossed corticostriatal pyramidal cell subtypes, while SOM/LTS cells form projection-specific inhibitory connections
section_id
section_07_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
effect_size
FS cells connected nonselectively; LTS/SOM cells formed projection-specific connections
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
rat frontal cortex layer 5, in vitro paired recordings
section_title
Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
evidence_summary
Paired intracellular recordings in rat frontal cortex L5 between identified projection neurons and interneuron subtypes
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
single study
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1093/cercor/bhx276",
  "claim": "In layer 5 frontal cortex, FS/PV cells make nonselective connections with both corticopontine and crossed corticostriatal pyramidal cell subtypes, while SOM/LTS cells form projection-specific inhibitory connections",
  "evidence": "Paired intracellular recordings in rat frontal cortex L5 between identified projection neurons and interneuron subtypes",
  "effect_size": "FS cells connected nonselectively; LTS/SOM cells formed projection-specific connections",
  "text_access": "fulltext",
  "study_system": "rat frontal cortex layer 5, in vitro paired recordings",
  "replication_status": "single study",
  "claim_source_sentence": "LTS subgroups differently inhibited the PC subtypes, although FS cells made nonselective connections with both projection subtypes. These results demonstrate a novel recurrent network of inhibitory and projection-specific excitatory neurons within the neocortex.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "LTS subgroups differently inhibited the PC subtypes, although FS cells made nonselective connections with both projection subtypes."
}
source_refs
[
  "paper:paper-aa18bb0de98d"
]
source_span
LTS subgroups differently inhibited the PC subtypes, although FS cells made nonselective connections with both projection subtypes. These results demonstrate a novel recurrent network of inhibitory and projection-specific excitatory neurons within the neocortex.
evidence_refs
[
  {
    "ref": "paper:paper-aa18bb0de98d"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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