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- Live5/17/2026, 4:35:28 PM
8ca06d3cbfb4Content snapshot
{ "scope": "rat frontal cortex layer 5, in vitro paired recordings", "claim_text": "In layer 5 frontal cortex, FS/PV cells make nonselective connections with both corticopontine and crossed corticostriatal pyramidal cell subtypes, while SOM/LTS cells form projection-specific inhibitory connections", "raw_fields": { "n": 0, "doi": "10.1093/cercor/bhx276", "claim": "In layer 5 frontal cortex, FS/PV cells make nonselective connections with both corticopontine and crossed corticostriatal pyramidal cell subtypes, while SOM/LTS cells form projection-specific inhibitory connections", "evidence": "Paired intracellular recordings in rat frontal cortex L5 between identified projection neurons and interneuron subtypes", "effect_size": "FS cells connected nonselectively; LTS/SOM cells formed projection-specific connections", "text_access": "fulltext", "study_system": "rat frontal cortex layer 5, in vitro paired recordings", "replication_status": "single study", "claim_source_sentence": "LTS subgroups differently inhibited the PC subtypes, although FS cells made nonselective connections with both projection subtypes. These results demonstrate a novel recurrent network of inhibitory and projection-specific excitatory neurons within the neocortex.", "replication_evidence_dois": [], "effect_size_source_sentence": "LTS subgroups differently inhibited the PC subtypes, although FS cells made nonselective connections with both projection subtypes." }, "section_id": "section_07_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json", "effect_size": "FS cells connected nonselectively; LTS/SOM cells formed projection-specific connections", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-07", "source_kind": "review_finding", "source_path": "evidence/section_07_evidence_package.json", "source_refs": [ "paper:paper-aa18bb0de98d" ], "source_span": "LTS subgroups differently inhibited the PC subtypes, although FS cells made nonselective connections with both projection subtypes. These results demonstrate a novel recurrent network of inhibitory and projection-specific excitatory neurons within the neocortex.", "study_system": "rat frontal cortex layer 5, in vitro paired recordings", "evidence_refs": [ { "ref": "paper:paper-aa18bb0de98d" } ], "section_title": "Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Paired intracellular recordings in rat frontal cortex L5 between identified projection neurons and interneuron subtypes", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "single study", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-07", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }