- claim_text
An optimal trade-off model between wiring cost and processing efficiency reproduces ~67% of macaque cortical connections, exceeding the ~56% explained by a generative model combining spatial distance and topological similarity, indicating cost-efficiency as a major driver of primate intra-cortical wiring.
- raw_fields
{
"n": 0,
"doi": "10.1371/journal.pcbi.1005776",
"claim": "An optimal trade-off model between wiring cost and processing efficiency reproduces ~67% of macaque cortical connections, exceeding the ~56% explained by a generative model combining spatial distance and topological similarity, indicating cost-efficiency as a major driver of primate intra-cortical wiring.",
"cite_key": "Chen2017",
"evidence": "An optimal trade-off model between wiring cost and processing efficiency reproduces ~67% of macaque cortical connections, exceeding the ~56% explained by a generative model combining spatial distance and topological similarity, indicating cost-efficiency as a major driver of primate intra-cortical wiring.",
"effect_size": "67%",
"text_access": "fulltext",
"study_system": "Macaque cortical connectome (Markov–Kennedy weighted directed dataset)",
"source_cluster_id": "cluster_07",
"replication_status": "replication_unknown",
"claim_source_sentence": "The primate connectome indeed displays a cost-efficiency trade-off and that up to 67% of the connections were recovered by optimal combination of the two basic factors of wiring economy and processing efficiency, clearly higher than the proportion of connections (56%) explained by the generative model.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "The primate connectome indeed displays a cost-efficiency trade-off and that up to 67% of the connections were recovered by optimal combination of the two basic factors of wiring economy and processing efficiency, clearly higher than the proportion of connections (56%) explained by the generative model."
}- source_refs
[
"paper:paper-0fedbe69b829"
]
- source_span
The primate connectome indeed displays a cost-efficiency trade-off and that up to 67% of the connections were recovered by optimal combination of the two basic factors of wiring economy and processing efficiency, clearly higher than the proportion of connections (56%) explained by the generative model.
- evidence_refs
[
{
"ref": "paper:paper-0fedbe69b829"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}- evidence_summary
An optimal trade-off model between wiring cost and processing efficiency reproduces ~67% of macaque cortical connections, exceeding the ~56% explained by a generative model combining spatial distance and topological similarity, indicating cost-efficiency as a major driver of primate intra-cortical wiring.