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- Live5/17/2026, 4:35:28 PM
79d1deef02bbContent snapshot
{ "scope": "Macaque cortical connectome (Markov–Kennedy weighted directed dataset)", "claim_text": "An optimal trade-off model between wiring cost and processing efficiency reproduces ~67% of macaque cortical connections, exceeding the ~56% explained by a generative model combining spatial distance and topological similarity, indicating cost-efficiency as a major driver of primate intra-cortical wiring.", "raw_fields": { "n": 0, "doi": "10.1371/journal.pcbi.1005776", "claim": "An optimal trade-off model between wiring cost and processing efficiency reproduces ~67% of macaque cortical connections, exceeding the ~56% explained by a generative model combining spatial distance and topological similarity, indicating cost-efficiency as a major driver of primate intra-cortical wiring.", "cite_key": "Chen2017", "evidence": "An optimal trade-off model between wiring cost and processing efficiency reproduces ~67% of macaque cortical connections, exceeding the ~56% explained by a generative model combining spatial distance and topological similarity, indicating cost-efficiency as a major driver of primate intra-cortical wiring.", "effect_size": "67%", "text_access": "fulltext", "study_system": "Macaque cortical connectome (Markov–Kennedy weighted directed dataset)", "source_cluster_id": "cluster_07", "replication_status": "replication_unknown", "claim_source_sentence": "The primate connectome indeed displays a cost-efficiency trade-off and that up to 67% of the connections were recovered by optimal combination of the two basic factors of wiring economy and processing efficiency, clearly higher than the proportion of connections (56%) explained by the generative model.", "replication_evidence_dois": [], "effect_size_source_sentence": "The primate connectome indeed displays a cost-efficiency trade-off and that up to 67% of the connections were recovered by optimal combination of the two basic factors of wiring economy and processing efficiency, clearly higher than the proportion of connections (56%) explained by the generative model." }, "section_id": "section_08", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_08_evidence_package.json", "effect_size": "67%", "review_repo": "ComputationalReviewLoops", "section_ref": "wiki_page:computationalreviewloops-08", "source_kind": "review_finding", "source_path": "evidence/section_08_evidence_package.json", "source_refs": [ "paper:paper-0fedbe69b829" ], "source_span": "The primate connectome indeed displays a cost-efficiency trade-off and that up to 67% of the connections were recovered by optimal combination of the two basic factors of wiring economy and processing efficiency, clearly higher than the proportion of connections (56%) explained by the generative model.", "study_system": "Macaque cortical connectome (Markov–Kennedy weighted directed dataset)", "evidence_refs": [ { "ref": "paper:paper-0fedbe69b829" } ], "section_title": "Cortical Association Connectome: Intra-Cortical Loops and Modules", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }, "evidence_summary": "An optimal trade-off model between wiring cost and processing efficiency reproduces ~67% of macaque cortical connections, exceeding the ~56% explained by a generative model combining spatial distance and topological similarity, indicating cost-efficiency as a major driver of primate intra-cortical wiring.", "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d49e54403ef9", "source_artifact_ref": "wiki_page:computationalreviewloops-08", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_08_evidence_package.json", "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }