- raw_fields
{
"n": 0,
"doi": "10.1523/jneurosci.0805-24.2024",
"claim": "Developmental postsynaptic t-LTD at L2/3-L2/3 synapses in mouse somatosensory cortex requires postsynaptic GluN2B-containing NMDARs and astrocyte-released d-serine acting on those NMDARs.",
"cite_key": "AndradeTalavera2024",
"evidence": "P13-P21 mice showed t-LTD at L2/3-L2/3 synapses by single pre-post pairings at 0.2 Hz; induction required postsynaptic Ca, internal Ca release, calcineurin, endocannabinoid CB1 signalling and astrocytic d-serine acting on GluN2B-containing NMDARs.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "Juvenile mouse somatosensory cortex L2/3-L2/3 synapses (slice, P13-P21)",
"argument_role": "supporting",
"replication_status": "replication_unknown",
"claim_source_sentence": "These results show direct evidence of the mechanism involved in developmental postsynaptic t-LTD at L2/3-L2/3 synapses, revealing a central role of astrocytes and their release of d-serine in its induction.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-f0807984e9f3"
]
- evidence_refs
[
{
"ref": "paper:paper-f0807984e9f3"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}- evidence_summary
P13-P21 mice showed t-LTD at L2/3-L2/3 synapses by single pre-post pairings at 0.2 Hz; induction required postsynaptic Ca, internal Ca release, calcineurin, endocannabinoid CB1 signalling and astrocytic d-serine acting on GluN2B-containing NMDARs.