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- Live5/17/2026, 4:35:28 PM
2e9a8be2d868Content snapshot
{ "scope": "biophysically constrained mouse V1 spiking column model", "claim_text": "A data-constrained mouse V1 spiking network with PV/SST/VIP cells lacks intrinsic rhythms but generates broad-band 15–60 Hz oscillations only after STDP-driven structural plasticity; feedforward inputs enhance and feedback inputs suppress these rhythms, and oscillation generation requires all four cell types.", "raw_fields": { "n": null, "doi": "10.3389/fncom.2025.1568143", "pmid": "40370493", "year": "2025", "claim": "A data-constrained mouse V1 spiking network with PV/SST/VIP cells lacks intrinsic rhythms but generates broad-band 15–60 Hz oscillations only after STDP-driven structural plasticity; feedforward inputs enhance and feedback inputs suppress these rhythms, and oscillation generation requires all four cell types.", "pmcid": "PMC12075120", "title": "Synaptic plasticity facilitates oscillations in a V1 cortical column model with multiple interneuron types.", "authors": "", "journal": "", "cite_key": "Moreni2025b", "evidence": "Spiking network simulation calibrated to mouse V1 firing rates; STDP added; oscillation power evaluated.", "cluster_id": "cluster_09_oscillations", "effect_size": "oscillations emerge in 15–60 Hz band only after plasticity", "figure_data": [], "text_access": "fulltext", "study_system": "biophysically constrained mouse V1 spiking column model", "cited_by_count": 5, "_source_cluster": "cluster_09_oscillations", "replication_status": "single-study", "_source_cluster_index": 15, "claim_source_sentence": "The resulting model matched in vivo cell-type-specific firing rates for spontaneous and stimulus-evoked conditions in mice, although rhythmic activity was absent. Upon introduction of long-term synaptic plasticity in the form of an STDP rule, broad-band (15-60 Hz) oscillations emerged, with feedforward/feedback input streams enhancing/suppressing the oscillatory drive, respectively. These plasticity-triggered rhythms relied on all cell types, and specific experience-dependent connectivity patterns were required to generate oscillations.", "replication_evidence_dois": [], "effect_size_source_sentence": "broad-band (15-60 Hz) oscillations emerged, with feedforward/feedback input streams enhancing/suppressing the oscillatory drive, respectively." }, "section_id": "section_10", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json", "effect_size": "oscillations emerge in 15–60 Hz band only after plasticity", "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-10-oscillatory-dynamics", "source_kind": "review_finding", "source_path": "evidence/section_10_evidence_package.json", "source_refs": [ "paper:paper-b58ecaabd35b" ], "source_span": "The resulting model matched in vivo cell-type-specific firing rates for spontaneous and stimulus-evoked conditions in mice, although rhythmic activity was absent. Upon introduction of long-term synaptic plasticity in the form of an STDP rule, broad-band (15-60 Hz) oscillations emerged, with feedforward/feedback input streams enhancing/suppressing the oscillatory drive, respectively. These plasticity-triggered rhythm...", "study_system": "biophysically constrained mouse V1 spiking column model", "evidence_refs": [ { "ref": "paper:paper-b58ecaabd35b" } ], "section_title": "Oscillatory Dynamics and Temporal Coordination", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Spiking network simulation calibrated to mouse V1 firing rates; STDP added; oscillation power evaluated.", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "single-study", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-10-oscillatory-dynamics", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }