Version history

{
  "scope": "Mouse auditory cortex and posterior striatum; retrograde tracing and optogenetic dissection of L4→striatum projection",
  "claim_text": "The mouse auditory cortex sends a direct long-range projection from layer-4 corticostriatal pyramidal neurons (CS-L4) to the posterior part of the dorsal striatum, where they engage parvalbumin-expressing striatal interneurons in a feedforward-inhibitory motif onto spiny projection neurons.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1523/jneurosci.1738-21.2021",
    "claim": "The mouse auditory cortex sends a direct long-range projection from layer-4 corticostriatal pyramidal neurons (CS-L4) to the posterior part of the dorsal striatum, where they engage parvalbumin-expressing striatal interneurons in a feedforward-inhibitory motif onto spiny projection neurons.",
    "cite_key": "Bertero2022",
    "evidence": "Anatomical tracing, in vitro electrophysiology and optogenetic mapping in mouse auditory cortex and posterior striatum.",
    "effect_size": "Existence and connectivity of CS-L4 → posterior striatum projection (qualitative); thalamus → L4 → striatum motif established.",
    "text_access": "abstract_only",
    "study_system": "Mouse auditory cortex and posterior striatum; retrograde tracing and optogenetic dissection of L4→striatum projection",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "The CS-L4 neurons are embedded in a feedforward inhibitory circuit involving local parvalbumin neurons and establish connections in the posterior striatum in yet another feedforward inhibitory thalamo→cortico(L4)→striatal circuit which potentially contributes in controlling control the output of striatal spiny projection neurons.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "auditory cortex projects to the posterior part of the dorsal striatum via pyramidal neurons located in layer 4 (CS-L4 neurons)"
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "Existence and connectivity of CS-L4 → posterior striatum projection (qualitative); thalamus → L4 → striatum motif established.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-a5667e433556"
  ],
  "source_span": "The CS-L4 neurons are embedded in a feedforward inhibitory circuit involving local parvalbumin neurons and establish connections in the posterior striatum in yet another feedforward inhibitory thalamo→cortico(L4)→striatal circuit which potentially contributes in controlling control the output of striatal spiny projection neurons.",
  "study_system": "Mouse auditory cortex and posterior striatum; retrograde tracing and optogenetic dissection of L4→striatum projection",
  "evidence_refs": [
    {
      "ref": "paper:paper-a5667e433556"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Anatomical tracing, in vitro electrophysiology and optogenetic mapping in mouse auditory cortex and posterior striatum.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}