- claim_text
The mouse auditory cortex sends a direct long-range projection from layer-4 corticostriatal pyramidal neurons (CS-L4) to the posterior part of the dorsal striatum, where they engage parvalbumin-expressing striatal interneurons in a feedforward-inhibitory motif onto spiny projection neurons.
- raw_fields
{
"n": 0,
"doi": "10.1523/jneurosci.1738-21.2021",
"claim": "The mouse auditory cortex sends a direct long-range projection from layer-4 corticostriatal pyramidal neurons (CS-L4) to the posterior part of the dorsal striatum, where they engage parvalbumin-expressing striatal interneurons in a feedforward-inhibitory motif onto spiny projection neurons.",
"cite_key": "Bertero2022",
"evidence": "Anatomical tracing, in vitro electrophysiology and optogenetic mapping in mouse auditory cortex and posterior striatum.",
"effect_size": "Existence and connectivity of CS-L4 → posterior striatum projection (qualitative); thalamus → L4 → striatum motif established.",
"text_access": "abstract_only",
"study_system": "Mouse auditory cortex and posterior striatum; retrograde tracing and optogenetic dissection of L4→striatum projection",
"argument_role": "supporting",
"replication_status": "single_study",
"claim_source_sentence": "The CS-L4 neurons are embedded in a feedforward inhibitory circuit involving local parvalbumin neurons and establish connections in the posterior striatum in yet another feedforward inhibitory thalamo→cortico(L4)→striatal circuit which potentially contributes in controlling control the output of striatal spiny projection neurons.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": "auditory cortex projects to the posterior part of the dorsal striatum via pyramidal neurons located in layer 4 (CS-L4 neurons)"
}- source_refs
[
"paper:paper-a5667e433556"
]
- source_span
The CS-L4 neurons are embedded in a feedforward inhibitory circuit involving local parvalbumin neurons and establish connections in the posterior striatum in yet another feedforward inhibitory thalamo→cortico(L4)→striatal circuit which potentially contributes in controlling control the output of striatal spiny projection neurons.
- evidence_refs
[
{
"ref": "paper:paper-a5667e433556"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}