Version history

{
  "scope": "mouse",
  "claim_text": "Synergistic deficits in parvalbumin interneurons and dopamine signaling drive ACC dysfunction in chronic pain — Chronic pain arises from maladaptive changes in both peripheral and central nervous systems, including the anterior cingulate cortex (ACC), a key region implica",
  "raw_fields": {
    "n": 0,
    "doi": "10.1073/pnas.2502558122",
    "claim": "Synergistic deficits in parvalbumin interneurons and dopamine signaling drive ACC dysfunction in chronic pain — Chronic pain arises from maladaptive changes in both peripheral and central nervous systems, including the anterior cingulate cortex (ACC), a key region implica",
    "title": null,
    "cite_key": "Lancon2025",
    "evidence": "Reported in Proceedings of the National Academy of Sciences of the United States of America (2025); from Body of abstract.",
    "effect_size": null,
    "text_access": "abstract_only",
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    "_source_cluster": "cluster_05_synaptic_connectivity",
    "replication_status": "replication_unknown",
    "_source_cluster_index": 388,
    "claim_source_sentence": "Chronic pain arises from maladaptive changes in both peripheral and central nervous systems, including the anterior cingulate cortex (ACC), a key region implicated in descending pain modulation.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
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  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
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  "review_repo": "ComputationalReviewVIP",
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  "source_span": "Chronic pain arises from maladaptive changes in both peripheral and central nervous systems, including the anterior cingulate cortex (ACC), a key region implicated in descending pain modulation.",
  "study_system": "mouse",
  "evidence_refs": [
    {
      "ref": "paper:paper-0acff15589a5"
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  "section_title": "Synaptic Properties and Connectivity",
  "source_policy": {
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    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
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  "evidence_summary": "Reported in Proceedings of the National Academy of Sciences of the United States of America (2025); from Body of abstract.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replication_unknown",
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  "source_artifact_ref": "wiki_page:computationalreviewvip-06-synaptic-properties",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
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