Version history

{
  "scope": "Mouse C2 barrel column; in vitro slices",
  "claim_text": "Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms).",
  "raw_fields": {
    "n": 0,
    "doi": "10.1093/cercor/bhx094",
    "claim": "Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms).",
    "cite_key": "Lefort2017",
    "evidence": "Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms).",
    "effect_size": "30 ms",
    "text_access": "abstract_only",
    "study_system": "Mouse C2 barrel column; in vitro slices",
    "source_cluster_id": "cluster_07",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Synaptic transmission between any given pair of neurons is typically a dynamic process with presynaptic action potentials (APs) evoking depressing or facilitating postsynaptic potentials when presynaptic APs occur within hundreds of milliseconds of each other.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms)."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_08_evidence_package.json",
  "effect_size": "30 ms",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-08",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-1f2e0ebd9f4c"
  ],
  "source_span": "Synaptic transmission between any given pair of neurons is typically a dynamic process with presynaptic action potentials (APs) evoking depressing or facilitating postsynaptic potentials when presynaptic APs occur within hundreds of milliseconds of each other.",
  "study_system": "Mouse C2 barrel column; in vitro slices",
  "evidence_refs": [
    {
      "ref": "paper:paper-1f2e0ebd9f4c"
    }
  ],
  "section_title": "Cortical Association Connectome: Intra-Cortical Loops and Modules",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms).",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-08",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_08_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}