- claim_text
Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms).
- raw_fields
{
"n": 0,
"doi": "10.1093/cercor/bhx094",
"claim": "Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms).",
"cite_key": "Lefort2017",
"evidence": "Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms).",
"effect_size": "30 ms",
"text_access": "abstract_only",
"study_system": "Mouse C2 barrel column; in vitro slices",
"source_cluster_id": "cluster_07",
"replication_status": "replication_unknown",
"claim_source_sentence": "Synaptic transmission between any given pair of neurons is typically a dynamic process with presynaptic action potentials (APs) evoking depressing or facilitating postsynaptic potentials when presynaptic APs occur within hundreds of milliseconds of each other.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms)."
}- source_refs
[
"paper:paper-1f2e0ebd9f4c"
]
- source_span
Synaptic transmission between any given pair of neurons is typically a dynamic process with presynaptic action potentials (APs) evoking depressing or facilitating postsynaptic potentials when presynaptic APs occur within hundreds of milliseconds of each other.
- evidence_refs
[
{
"ref": "paper:paper-1f2e0ebd9f4c"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}- evidence_summary
Short-term synaptic dynamics between excitatory neurons in the mouse C2 barrel column are layer-dependent, with depression dominant at most connections but layer-2 presynaptic neurons preferentially producing facilitating output at short interspike intervals (10–30 ms).