Version history

{
  "scope": "Young-adult mouse higher visual areas V1b/LM/AL/PM (in vivo two-photon, MD paradigm)",
  "claim_text": "Monocular deprivation in young-adult mice produces ocular-dominance shifts in higher visual areas (LM, AL, PM) that are not uniform and are not simply inherited from V1: OD shifts are largest in LM and smallest in AL/PM, with different relative contributions of deprived- vs non-deprived-eye changes.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1093/cercor/bhad203",
    "claim": "Monocular deprivation in young-adult mice produces ocular-dominance shifts in higher visual areas (LM, AL, PM) that are not uniform and are not simply inherited from V1: OD shifts are largest in LM and smallest in AL/PM, with different relative contributions of deprived- vs non-deprived-eye changes.",
    "cite_key": "Craddock2023",
    "evidence": "Two-photon calcium imaging in V1b, LM, AL, PM of young-adult mice across MD and recovery showed area-specific OD shift magnitudes and recovery dynamics; only V1 recovered to pre-MD OD index within 2 weeks.",
    "effect_size": "OD index recovery to baseline within 2 weeks only in V1",
    "text_access": "abstract_only",
    "study_system": "Young-adult mouse higher visual areas V1b/LM/AL/PM (in vivo two-photon, MD paradigm)",
    "argument_role": "supporting",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "OD shifts following MD were greatest in LM and smallest in AL and PM; in LM and AL, these shifts were mediated primarily through a reduction of deprived-eye responses, in V1b and LM through an increase in response through the non-deprived eye.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "The OD index recovered to pre-MD levels within 2 weeks in V1 only."
  },
  "section_id": "section_12",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_12_evidence_package.json",
  "effect_size": "OD index recovery to baseline within 2 weeks only in V1",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-12-plasticity",
  "source_kind": "review_finding",
  "source_path": "evidence/section_12_evidence_package.json",
  "source_refs": [
    "paper:paper-b42bc36d7d4a"
  ],
  "source_span": "OD shifts following MD were greatest in LM and smallest in AL and PM; in LM and AL, these shifts were mediated primarily through a reduction of deprived-eye responses, in V1b and LM through an increase in response through the non-deprived eye.",
  "study_system": "Young-adult mouse higher visual areas V1b/LM/AL/PM (in vivo two-photon, MD paradigm)",
  "evidence_refs": [
    {
      "ref": "paper:paper-b42bc36d7d4a"
    }
  ],
  "section_title": "12. Plasticity at E→E synapses in mouse — Hebbian, STDP, behavioural-time-scale plasticity; how plasticity shapes the recurrent matrix during learning",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Two-photon calcium imaging in V1b, LM, AL, PM of young-adult mice across MD and recovery showed area-specific OD shift magnitudes and recovery dynamics; only V1 recovered to pre-MD OD index within 2 weeks.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-12-plasticity",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_12_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}