Version history

{
  "scope": "Mouse mesoscale MPF connectome; DP/DPd/DPs and infralimbic projections to hypothalamic and brainstem visceromotor targets",
  "claim_text": "Integrated neuroanatomical, physiological, and behavioural mapping of the mouse medial prefrontal cortex identifies the dorsal peduncular area (DP), with deep (DPd) and superficial (DPs) layers, as a major component of the visceromotor cortex projecting directly to hypothalamic and brainstem structures.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/s41586-025-09360-w",
    "claim": "Integrated neuroanatomical, physiological, and behavioural mapping of the mouse medial prefrontal cortex identifies the dorsal peduncular area (DP), with deep (DPd) and superficial (DPs) layers, as a major component of the visceromotor cortex projecting directly to hypothalamic and brainstem structures.",
    "cite_key": "Hintiryan2025b",
    "evidence": "DP functions as a network hub integrating diverse cortical inputs and modulating goal-directed behaviour through largely unidirectional cortical information flow; mesoscale MPF connectome supports a unified model.",
    "effect_size": null,
    "text_access": "abstract_only",
    "study_system": "Mouse mesoscale MPF connectome; DP/DPd/DPs and infralimbic projections to hypothalamic and brainstem visceromotor targets",
    "source_cluster_id": "cluster_11",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "Here, using integrated neuroanatomical, physiological and behavioural approaches, we construct a comprehensive wiring diagram of the MPF, focused on the dorsal peduncular area (DP)-a poorly understood prefrontal area.",
    "replication_evidence_dois": [
      "10.1038/s41586-021-03993-3",
      "10.1038/s41467-021-22915-5"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_12",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-12",
  "source_kind": "review_finding",
  "source_path": "evidence/section_12_evidence_package.json",
  "source_refs": [
    "paper:paper-dea7638ea150"
  ],
  "source_span": "Here, using integrated neuroanatomical, physiological and behavioural approaches, we construct a comprehensive wiring diagram of the MPF, focused on the dorsal peduncular area (DP)-a poorly understood prefrontal area.",
  "study_system": "Mouse mesoscale MPF connectome; DP/DPd/DPs and infralimbic projections to hypothalamic and brainstem visceromotor targets",
  "evidence_refs": [
    {
      "ref": "paper:paper-dea7638ea150"
    }
  ],
  "section_title": "Whole-Brain Connectomics: Mouse, Primate, Human",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "DP functions as a network hub integrating diverse cortical inputs and modulating goal-directed behaviour through largely unidirectional cortical information flow; mesoscale MPF connectome supports a unified model.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-12",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}