Version history

{
  "scope": "Adult mouse whole brain; CCFv3 augmented atlas + Nissl template at 10 μm",
  "claim_text": "The Blue Brain Project CCFv3 augmented atlas (CCFv3_BBP) extends the Allen CCFv3 to fully annotate the most rostral and caudal mouse-brain regions (main olfactory bulb, cerebellum, medulla) and provides an improved Nissl reference volume aligned to the new atlas.",
  "raw_fields": {
    "n": 734,
    "doi": "10.1162/imag_a_00565",
    "claim": "The Blue Brain Project CCFv3 augmented atlas (CCFv3_BBP) extends the Allen CCFv3 to fully annotate the most rostral and caudal mouse-brain regions (main olfactory bulb, cerebellum, medulla) and provides an improved Nissl reference volume aligned to the new atlas.",
    "cite_key": "Piluso2025",
    "evidence": "734 Nissl-stained brains aligned to generate a 10-μm average Nissl template; first comprehensive in silico whole-mouse-CNS cell-distribution model built on the enhanced atlas.",
    "effect_size": "734 Nissl brains aligned at 10-μm resolution",
    "text_access": "abstract_only",
    "study_system": "Adult mouse whole brain; CCFv3 augmented atlas + Nissl template at 10 μm",
    "source_cluster_id": "cluster_11",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "To overcome these limitations, we developed the Blue Brain Project (BBP) CCFv3 augmented atlas (CCFv3<sub>BBP</sub>), which includes a fully annotated mouse brain and an improved Nissl-stained reference volume aligned with the CCFv3<sub>BBP</sub>.",
    "replication_evidence_dois": [
      "10.1016/j.cell.2020.04.007",
      "10.1038/s41467-024-53254-w"
    ],
    "effect_size_source_sentence": "This enhanced atlas also features the central nervous system annotation."
  },
  "section_id": "section_12",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json",
  "effect_size": "734 Nissl brains aligned at 10-μm resolution",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-12",
  "source_kind": "review_finding",
  "source_path": "evidence/section_12_evidence_package.json",
  "source_refs": [
    "paper:paper-3cf435c26092"
  ],
  "source_span": "To overcome these limitations, we developed the Blue Brain Project (BBP) CCFv3 augmented atlas (CCFv3<sub>BBP</sub>), which includes a fully annotated mouse brain and an improved Nissl-stained reference volume aligned with the CCFv3<sub>BBP</sub>.",
  "study_system": "Adult mouse whole brain; CCFv3 augmented atlas + Nissl template at 10 μm",
  "evidence_refs": [
    {
      "ref": "paper:paper-3cf435c26092"
    }
  ],
  "section_title": "Whole-Brain Connectomics: Mouse, Primate, Human",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "734 Nissl-stained brains aligned to generate a 10-μm average Nissl template; first comprehensive in silico whole-mouse-CNS cell-distribution model built on the enhanced atlas.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-12",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}