Version history

{
  "scope": "Mouse vS1 ↔ vM1; CRACM circuit mapping.",
  "claim_text": "CRACM mapping in mouse barrel cortex and vibrissal motor cortex shows that vS1 axons preferentially target upper-layer L2/3 and L5A pyramidal neurons in vM1 (including neurons projecting back to vS1) and only weakly target deeper L5B and L6, defining laminar logic of the S1↔M1 cortico-cortical loop.",
  "raw_fields": {
    "n": null,
    "doi": "10.1016/j.neuron.2011.07.029",
    "claim": "CRACM mapping in mouse barrel cortex and vibrissal motor cortex shows that vS1 axons preferentially target upper-layer L2/3 and L5A pyramidal neurons in vM1 (including neurons projecting back to vS1) and only weakly target deeper L5B and L6, defining laminar logic of the S1↔M1 cortico-cortical loop.",
    "cite_key": "Mao2011",
    "evidence": "ChR2 expression + anterograde and retrograde labelling + CRACM mapping of cortico-cortical synaptic strength between mouse vS1 and vM1.",
    "effect_size": "S1→M1 input strongest in L2/3 and L5A; particularly strong onto M1→S1-projecting cells; weaker input to L5B/L6.",
    "text_access": "abstract_only",
    "study_system": "Mouse vS1 ↔ vM1; CRACM circuit mapping.",
    "argument_role": "supporting",
    "replication_status": "replicated",
    "claim_source_sentence": "Barrel cortex axons preferentially targeted upper layer (L2/3, L5A) neurons in motor cortex; input to neurons projecting back to barrel cortex was particularly strong.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1038/nature11321"
    ],
    "effect_size_source_sentence": "Barrel cortex axons preferentially targeted upper layer (L2/3, L5A) neurons in motor cortex; input to neurons projecting back to barrel cortex was particularly strong."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "effect_size": "S1→M1 input strongest in L2/3 and L5A; particularly strong onto M1→S1-projecting cells; weaker input to L5B/L6.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:fcc61ea6-0808-4982-bba8-392f7abe074f"
  ],
  "source_span": "Barrel cortex axons preferentially targeted upper layer (L2/3, L5A) neurons in motor cortex; input to neurons projecting back to barrel cortex was particularly strong.",
  "study_system": "Mouse vS1 ↔ vM1; CRACM circuit mapping.",
  "evidence_refs": [
    {
      "ref": "paper:fcc61ea6-0808-4982-bba8-392f7abe074f"
    }
  ],
  "section_title": "8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "ChR2 expression + anterograde and retrograde labelling + CRACM mapping of cortico-cortical synaptic strength between mouse vS1 and vM1.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}